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Rev. 33, 18–29 (2017). Article CAS PubMed Google Scholar Ungricht, R. & Kutay, U. Mechanisms and functions of nuclear envelope remodelling. Nat. Rev. Mol. Cell Biol. 18, 229–245 (2017). Article CAS PubMed Google Scholar Burke, B. & Stewart, C. L. The nuclear lamins: ...
To elucidate the impact of NAT10 on tumor immunity, CyTOF analysis was performed on 4T1 tumor tissues. t-Distributed stochastic neighbor embedding (t-SNE) analysis of CyTOF data revealed 8 distinct intertumoral immune cell populations, with the majority comprising T cells and macrophages (Fig. 3A...
a, Western blotting showing the knockdown efficiency of NAT10 in MOLM13 cells on day 4 post lentiviral shRNA transduction.b, Methylthialazole tetrazolium (MTT) assays showing the effects of NAT10 knockdown on cell proliferation in MOLM13 cells.c, Volcano plots showing DEGs in MOLM13 cells on ...
Cytoplasmic NMNAT2 has been recently described as an axon survival factor, a role which is linked to its enzymatic activity, while NMNAT1 appears to have a similar function in neuronal cell bodies [6]. The discovery that loss-of-function mutations in the nuclear isoform NMNAT1 cause Leber ...
Mol. Cell. Biol., 23 (2003), pp. 7403-7414 View in ScopusGoogle Scholar Geissenhöner et al., 2004 A. Geissenhöner, C. Weise, A.E. Ehrenhofer-Murray Dependence of ORC silencing function on NatA-mediated Nalpha acetylation in Saccharomyces cerevisiae Mol. Cell. Biol., 24 (2004),...
Such undifferentiated cells can be infected by HIV-I and HIV-2 strains without affecting cell growth. In differentiated cells, the CD4-1ike mol- ecules are restricted to the basolateral membrane domain, although such cells can be infected with HIV at the apical brush border membrane (lumi- ...
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PLKO.1 vector plasmids carrying shRNA targeting mouse Nat1 (5′-CCAACTAATGACTTGTTGTAT-3′) or scrambled sequence (5′-CAACAAGATGAAGAGCACCAA-3′) were individually transfected into 293T cells with VSVG, REV and MDL plasmids for 8 hours and then cell medium was changed to remove transfection...
polymers Article Molecular Weight-Dependent Activity of Aminated Poly(α)glutamates as siRNA Nanocarriers Adva Krivitsky 1, Vadim Krivitsky 2, Dina Polyak 1,3 ID , Anna Scomparin 1 ID , Shay Eliyahu 1, Hadas Gibori 1, Eilam Yeini 1, Evgeni Pisarevsky 1, Rachel Blau 1 and Ronit Satchi...