More than 170,000 sequences were obtained (∼ 5,000 sequences per sample with averaged sequence length ∼ 450 bp). The taxonomical assignment for the sequences using both RDP Classifier and BLAST showed that there were 2 kingdoms; 18 phyla; 27 classes; 53 orders; 96 families; 256 ...
THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria. Phenotypic screens for bactericidal compounds against drug-resistant tuberculosis are beginning to yield novel inhibitors. However, reliable target identif... AG Jonathan,Cox,A Katherine,... - 《Nature Microbiology...
While the majority of modulated phosphosites currently have no functional assignment29, gene ontology (GO) enrichment analysis revealed that phosphoproteins regulated by elevated cardiac BCKA exposure are significantly overrepresented in regions such as the actin cytoskeleton, actomyosin, and contractile act...
The latter twopairs are located in a closed loop of 14 amino acids, byvirtue of the fact that half-cystinyl residues V and VI areseparated by only a single residue in the linear sequence.Assignment of the side-chain amides showed that 7 of 11aspartic acid residues and 2 of 8 glutamic ...
The assignment of all the mice to different drugs was randomised (Experiment 1: n = 10 for saline, n = 9 for MK801, and n = 10 for scopolamine; Experiment 2: n = 9 per drug group) using a Williams Square design [25]. 2.5. Apparatus and Testing Protocols Upon behavioural testing ...