Any Hong Kong registered company must fill in, signed and deliver the NAR1 form (Annual Return form) with the annual registration fee within 42 days after the date of return. Any late delivery (or submission) is subject to payment of a higher registration fee (or penalty). ...
Interferon alpha and beta receptor subunit 1 (IFNAR1) is a type I membrane protein that associates with IFNAR2 to form the receptor for type I interferons, including interferons-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus protein kinases, which in turn ...
Interferon alpha and beta receptor subunit 1 (IFNAR1) is a type I membrane protein that associates with IFNAR2 to form the receptor for type I interferons, including interferons-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus protein kinases, which in turn ...
Gene expression analysis was performed by using the Applied Biosystems 1700 microarray plat- form and the Human Genome Survey Microarray V2.0 containing 32 878 unique 60-mer oligonucleotide probes (Applied Biosystems). A 1-mg of total RNA was amplified and converted to digoxigenin-labeled cRNA by ...
1E). However, the addition of IFN-β to IFNAR1-SD12 did not alter the mobility of this form of IFNAR1-ECD, indicating that IFN-β did not bind this protein efficiently under these conditions (Fig. 1E). These data suggest that under native PAGE conditions the presence of SD3 of IF...
The physiological relevance of this in vitro analysis is supported by the finding that in 11,1 cells, a mutant form of Tyk2 lacking amino acids 1–21 was as functional as the wild-type protein,i.e. it restored IFNAR1 levels, ligand binding, induced gene expression, and antiviral ...
WorkItemFormControlcan be used to display and edit work items. This control reads an XML form definition which specifies the type and layout of the controls on the form. Each work item type has an associated form definition (exposed in the object model asWorkItem.Type.Displ...
Once inside the cytoplasm + sense RNA is read by ribosomes to make viral proteins and acting as a template to form an intermediate hybrid state with negative sense RNA to facilitate making multiple copies of the original + ssRNA. Thus significant dsRNA is present for a period, which allows ...