Nanozymes: a clear definition with fuzzy edges. Nano Today 40, 101269 (2021). Article Google Scholar Zandieh, M. & Liu, J. Nanozymes: definition, activity, and mechanisms. Adv. Mater. 36, 2211041 (2023). Articl
Nanozymes can be defined as nanomaterials with intrinsic enzyme-like activity that catalyze the conversion of substrates by following the same kinetics and mechanisms as natural enzymes under physiological conditions. From: Applications of Nanomaterials, 2018 ...
exploration their enzyme-like activities and catalytic mechanisms (e.g., “gold nanoparticles”, “catalytic activity”, “nanomaterials”) until around 2018. It gradually expanded
This nanozyme platforms possess remarkable catalytic activity and environmental specificity. ROS and RNS were effectively scavenged by the catalytic activity of triM system. Importantly, the triM nanozyme favors neutral environments in counteracting OH, 1O2, and NO radicals, which exhibits its catalytic ...
and the term “nanozyme” was introduced by Scrimin et al. in 2004 [5]. The field gained significant attention in 2007 [6], when Yan et al. discovered that ferromagnetic nanoparticles possess enzyme-like activity. Since then, considerable research attention has focused on nanozymes, producing ...
Nanozymes are nanomaterials that catalyze the conversion of the same substrates to products as their corresponding enzymes and follow enzyme kinetics under physiologically conditions, regardless of whether they have the same molecular mechanisms with their enzyme counterparts. Nanozymes are regarded as next-...
[41]. In addition, the activity of CAT-like NMNZs is also highly dependent on pH and temperature [9,42]. Although most favor neutral or alkaline conditions, a few CAT-like BMNZs prefer slightly acidic environments. The underlying catalytic mechanisms of CAT-like BMNZs are poorly understood....
The cell-damaging effects of pro-oxidant nanozymes can be used in fighting tumours and bacterial infections. When designing nanozymes for in vivo applications, structural and surface properties should be considered alongside their catalytic activity as well as the disease microenvironment and their interac...
(SOD-like) activity41. However, the selectivity of these biocatalysts merely relies on the specific atomic coordination and surface ligands of individual nanosystems, making it difficult to corroborate a universal catalytic mechanism explicitly. Besides, the complexity of reaction pathways also compromises...
Nanozymes, a category of nanomaterials with enzyme-like activity, have garnered growing interest in various biomedical contexts. Notably, nanozymes that are capable of regulating reactive oxygen species levels by emulating antioxidant or prooxidant enzym