Nanoparticle Technology for Drug Deliverydoi:10.1201/9780849374555.ch8Mahesh ChaubalBarrett RabinowRabinow B, Chaubal MV. Injectable nanoparticles for efficient drug delivery. Drugs Pharmaceut Sci. 2006;159:199-229.B. Rabinow, M.V. Chaubal, Injectable nanoparticles for efficient drug delivery, Drugs...
Lipid nanoparticles (LNPs) for the efficient delivery of drugs need to be designed for the particular administration route and type of drug. Here we report the design of LNPs for the efficient delivery of therapeutic RNAs to the lung via nebulization. We optimized the composition, molar ratios ...
Owing to these supramolecular structure, the polymeric self-aggregates have been considered one of the promising candidates for drug carriers with higher drug concentration in an aqueous milieu than to the solubility limit of the hydrophobic free drug by partitioning the drugs into the hydrophobic ...
Choi C, Chae SY, Nah J-W: Thermosensitive poly(N-isopropylacrylamide)-b-poly([epsilon]-caprolactone) nanoparticles for efficient drug delivery system. Polymer. 2006, 47 (13): 4571-4580. Article CAS Google Scholar Kim SY, Lee YM: Taxol-loaded block copolymer nanospheres composed of methoxy ...
The surface functionalization of nanoparticles with various types of ligands with chemical or biological activity is a powerful tool for efficient drug delivery. These multifunctional nanoparticles have significant potential for overcoming complex physiological barriers and increasing the targeting efficiency of ...
Chapter 1 Nanotechnology: Bridging Aspects of Catalysis, Energy and Drug Delivery Ramesh S. Chaughule and Anant R. Kapdi Chapter 2 Shape and Size Dependent Catalysis by Metallic Nanoparticles B. Viswanathan Chapter 3 Nanostructuring of Carbon-Platinum Composites for Efficient Catalytic Oxidation of ...
Nanoparticle based dermal drug delivery is attractive and non-invasive for preventing or treating localized cutaneous cancers. This is especially beneficial for patients that are not viable for surgery or highly intensive non-specific systemic therapies. When designed and engineered optimally, nanoparticle-...
Naturally occurring melanin-based nanoparticles (MNPs) are developed as a highly efficient and biocompatible nanoplatform for drug delivery for cancer imaging-guided treatment. Specifically the FDA-approved drug Sorafenib, which has high hydrophobicity, is successfully loaded into MNPs to prepare a water-...
In addition, the vast majority of molecules in a nanostructure reside at the particle surface,[4] which maximizes the loading and delivery of cargos, such as therapeutic drugs, proteins and polynucleotides, to targeted cells and tissues. Highly efficient drug delivery, based on nanomaterials, ...
Developing biomimetic nanoparticles without loss of the integrity of proteins remains a major challenge in cancer chemotherapy. Here, we develop a biocompatible tumor-cell-exocytosed exosome-biomimetic porous silicon nanoparticles (PSiNPs) as drug carrie