Antiviral activitySARS-CoV-2Targeted drug deliveryTargeted nanoparticlesRecently, a novel coronavirus, known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has raised global concerns, being the etiological agent of the current pandemic infectious coronavirus disease 2019 (COVID-19). ...
New antiviral drugs and new preventive antiviral strategies are a target of intense scientific interest. Thanks to their peculiar properties, nanomaterials play an important role in this field, and, in particular, among metallic materials, silver nanoparticles were demonstrated to be effective against a...
Several nanoparticles, including gold nanoparticles, silver nanoparticles, quantum dots, carbon dots, graphene oxide nanoparticles, and zinc oxide nanoparticles, have previously demonstrated remarkable antiviral activity against a diverse array of viruses. Objective This review aims to provide a basic and ...
siRNA acts as a broad-spectrum antiviral therapeutics directed to target multiple viral genotypes and strains in various organs. The RNA interference, propitiated by artificially created small interfering RNA (siRNA), is a possible strategy to repress RNA virus replication, presentation of viral antigen...
In combination the work represents a significant step forward in the development of next-gen adjuvants for improved anticancer and antiviral vaccines. More information:Natalia Muñoz-Wolf et al, Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles,Cell Reports Medicine(2023)...
Increasingly, clinical research has shown the potential of silica nanoparticles not only as an antiviral, but also its ability as a delivery system for antiviral small molecules and vaccines against viruses. Silica has an excellent biosafety profile and has been tested in several early phase clinical...
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Antiviral and anti-inflammatory treatment with multifunctional alveolar macrophage-like nanoparticles in a surrogate mouse model of COVID-19. Adv. Sci. (Weinh.) 8, 2003556 (2021). Google Scholar Wu, H. H., Zhou, Y., Tabata, Y. & Gao, J. Q. Mesenchymal stem cell-based drug delivery ...
Currently, HPV vaccines do not offer an effective treatment for women who already present with cervical disease, and recommended periodical cervical screenings are difficult to perform in countries and areas lacking medical resources. Our aim was to develop nanoparticles (NPs) based on poly (β-...