Nanomedicine targeting the tumor microenvironment: Therapeutic strategies to inhibit angiogenesis, remodel matrix, and modulate immune responses. J. Cell Immunother. 2016, 2, 69-78. [CrossRef]Siegler, E.L.; Kim, Y.J.; Wang, P. Nanomedicine targeting the tumor microenvironment: Therapeutic ...
Phages are known as human-safe nanosized viruses that specifically infect bacteria. This work shows that non-lytic filamentous phages displaying a PD-L1-binding peptide and a melanoma-targeting peptide can efficiently target tumours and inhibit tumour growth by blocking the immune checkpoint. ...
Nanotechnology in Brain Tumor Targeting AikateriniLalatsa, ...MaxO’Connor, inNanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors, 2018 5.8Towards a Cure for Brain Tumors: Nanotechnology in the Operating Room and in the Clinic ...
-mediated tumor-selective delivery of nanomedicines. Several alternative strategies, which include tumor vascular targeting, cell-mediated tumor targeting, iRGD-mediated tumor targeting, and locoregional delivery, therefore, have been proposed for EPR-independent tumor targeting (Fig.2).29,30,31 Fig. 2...
The EPR effect and beyond: strategies to improve tumor targeting and cancer nanomedicine treatment efficacy. Theranostics. 2020;10:7921–4. Article PubMed PubMed Central Google Scholar Norouzi M, Amerian M, Amerian M, et al. Clinical applications of nanomedicine in cancer therapy. Drug ...
not only the tumor-targeting ability of systemically administeredp53, but also the specificity for tumor tissue over normal tissue. However, in Senzer et al.’s publication it is not possible to estimate the time required for the NP to travel from the point of administration to the tumor. ...
tumor targeting; lipid–polymer hybrid nanoparticles; cancer therapy; 38.Design and Characterization of Spray-Dried Proliposomes for the Pulmonary Delivery of Curcumin 机译:喷雾干燥脱脂剂的设计与表征姜黄素的肺递送 作者:Islam M Adel;Mohamed F ElMeligy;Mohamed E A Abdelrahim;Amr Maged;AbdelFattah A...
(< 10 nm) can improve EPR-based tumor targeting and efficient renal clearance [188]. As for the delivery vehicle, the excellent bio-compatibility performance makes the liposome to be a suitable system for drug delivery [189]. In a previous study, the doxorubicin (DOX) and DOX-loaded ...
Targeting the TGF-β signaling pathway has been exploited to relieve immunosuppression in the tumor microenvironment. Here the authors describe the design of a nanoplatform integrating the TGF-β receptor 1 inhibitor LY2157299 and the ROS-responsive JQ1 pro-drug, promoting anti-tumor immune responses ...
In vivo targeting of metastatic breast cancer via tumor vasculature-specific nano-graphene oxide Biomaterials, Volume 104, 2016, pp. 361-371 Dongzhi Yang,…, Hao Hong Human amniotic fluid stem cells labeled with up-conversion nanoparticles for imaging-monitored repairing of acute lung injury Biomater...