the zebra fish (Danio rerio), mysids are used commonly as a model organism to assess the risk of nanomaterials to examine the aquatic toxicity for in vivo studies [200,201,202]. Studying the genotoxicity effects and physiological responses of aquatic animals exposed to nanomaterials is possible t...
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Drug nanoaggregates are particles that can deleteriously cause false positive results during drug screening efforts, but alternatively, they may be used to improve pharmacokinetics when developed for drug delivery purposes. The structural features of mol
Portland is a city of beer-lovers and beer-makers, from small-scale producers to major breweries. In recent years, a crop of nanobreweries has sprung up, their owners fermenting beer in garages, pulling pints in trailers and creating a community along th
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Currently, nanotechnology is considered as an economically viable tool to extend the shelf-life of fresh foods. Owing to their higher surface area per mass compared to larger particles opens up a new avenue for developing more stable and biologically active nanoformulations to extend the shelf-life...
Tumor immunotherapy has gradually become an ever-concrete strategy against cancer recent years, with several immunotherapeutic agents receiving approval from regulatory agencies for the treatment of various cancers. These agents include immune checkpoint inhibitors, chimeric antigen receptor (CAR) T-cell ther...
Fig. 5: B7-H3 nanobody-based CAR-T cells exhibit superior persistent antitumor activity against human pancreatic cancer in mice. aExperimental schema of the Panc-1 metastasis xenograft mouse model (created with BioRender.com).n = 7/8 mice/group.b,cRepresentative tumor bioluminescence images...