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5.利用Jetson Nano GPU训练模型(也可以使用自己的电脑训练这些数据,在后面章节中我们单独提出),在命令中输入sudo python3 ~/mycar/manage.pydrive --model ~/mycar/models/mypilot即可训练数据,以下是训练过程: 6.训练成功后会在Nano系统目录/home/xiaor/mycar/models下出现一个 mypilot文件,这个就是训练模型,运...
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Rational design of chimeric antigen receptor T (CAR-T) cells based on the recognition of antigenic epitopes capable of evoking the most potent CAR activation is an important objective in optimizing immune therapy. In solid tumors, the B7-H3 transmembrane
Carbon nanoparticles have garnered significant attention as nanovaccine carriers [42,52]. A new carbon nanoparticle that repels water, created by using silica as a model and sucrose as a source of carbon, has a diameter of 470 nm and pores measuring 40–60 nm, enabling it to hold a large...
CAR T-cell therapy could also bring up severe side effects, including cytokine release syndrome (CRS) and neurotoxicity [4]. In addition to these toxicities, there are also limitations related to the ability of these therapies to target solid tumors. While immunotherapy has made incredible ...
M. et al. Ionizable lipid nanoparticle-mediated mRNA delivery for human CAR T cell engineering. Nano Lett. 20, 1578–1589 (2020). ADS Google Scholar Yamankurt, G. et al. Exploration of the nanomedicine-design space with high-throughput screening and machine learning. Nat. Biomed. Eng. 3...
Herein, a new carrier-free nanoprodrug (i.e., Mn-ZnO2 nanoparticles) was developed for concurrent delivery of dual Zn-Mn ions and reactive oxygen species (ROS) within tumor to regulate the p53 protein for high anti-tumor efficacy. In response to the mild tumor acidic environment, the ...
Journal of Nanobiotechnology volume 21, Article number: 408 (2023) Cite this article 7451 Accesses 1 Altmetric Metrics details Abstract Marine resources in unique marine environments provide abundant, cost-effective natural biomaterials with distinct structures, compositions, and biological activities compared...