NAMPT Inhibitor Screening Assay Kit供应商 BPS Bioscience产品货号 BPS-71276-1产品报价 ￥询价/96rxns.产品说明书 点击查看购买方式 在线支付宝及网银支付、支票、现金、电汇,或拨打全国免费服务电话4006800868与我们联系.产品新闻背景资料 该NAMPT 抑制剂筛选检测试剂盒的背景资料请参阅该产品的英文说明书。产品...
保存条件:-80°C英文名:NAMPTInhibitorScreeningAssayKit数量:1供应商:BPSBioscienceInc 详情介绍 保存条件: -80°C 英文名: NAMPT Inhibitor Screening Assay Kit 数量: 1 供应商: BPS Bioscience Inc. CAS号: / 规格: 盒 The NAMPT Inhibitor Screening Assay Kit is designed to measure NAMPT activity for s...
烟酰胺磷酸核糖转移酶(Nicotinamide phosphoribosyltransferase,NAMPT)可催化烟酰胺(NAM)和磷酸核糖焦磷酸 (PRPP) 缩合为烟酰胺单核苷酸 (NMN),随后由烟酰胺单核苷酸腺苷酸转移酶(NMNAT)转化为烟酰胺腺嘌呤二核苷酸(NAD)。NAMPT是哺乳动物NAD生物合成中的限速酶,通过合成NAD,参与调节细胞内重要的生理病理过程。肿瘤细胞具...
2.14. Direct NAMPT activity assay in vitro Direct inhibition of NAMPT activity was evaluated using a NAMPT inhibitor screening assay kit (BPS Bioscience, 71276-1, US). All the samples and controls were tested in duplicate. PF403 was diluted with 5% DMSO to concentrations between 10–10 and 10...
IC50 was determined by log (inhibitor) vs. response using non-linear regression analysis. One-way ANOVA followed by Dunnet’s post-hoc test was used to interpret all the other parameters in the in vitro study, and data are represented as mean ± SEM of three independent experiments. ...
A chemical library (57,004 compounds) was screened for small molecules that bound to human NAMPT using a PTS assay (Fig.1a). The negative control was DMSO-treated NAMPT. The positive control was NAMPT treated with 20 μM CHS-828 (Fig.1b), a potent NAMPT inhibitor18. NAMPT ligands st...
Metabolic Inhibitors Screening Metabolic inhibitor library (Selleck, L5700) was purchased for this assay. Cells were pre-treated with inhibitors in 96-well plate for 24 hr. After anti-TCR stimulation for 16 hr, the surface levels of T cell activation markers were assessed using flow cytometry. ...