[6]Wang B,Hasan MK,Alvarado E,et al.NAMPT overexpression in prostate cancer and its contribution to tumor cell survival and stress response[J].Oncogene,2011,30:907-921. [7]Kim SR,Park HJ,Bae YH,et al.Curcumin down-regulates visfatin expression and inhibits breast cancer cell invasion[J]....
we tested NAMPT activity in the hippocampus, cortex, heart, liver, muscle, and kidney at 2, 6, and 12 months of age. We found that the activity of NAMPT in mouse tissues gradually decreased with increasing age. After nicotine administration in drinking water (2 μg/mL) from 6 to ...
NAMPT has been suggested association with atherosclerosis and insulin resistance. However, the impact of NAMPT on atherosclerosis remained unknown. Therefore, the objective of this study was to use a NAMPT loss-of-function approach to investigate the effect of NAMPT on atherosclerosis in hypercholestero...
Treatment options for acute myeloid leukemia (AML) remain extremely limited and associated with significant toxicity. Nicotinamide phosphoribosyltransferase (NAMPT) is involved in the generation of NAD+ and a potential therapeutic target in AML. We evaluated the effect of KPT-9274, a p21-activated ...
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. Exp Hematol. 2010;38:979–88. Article CAS PubMed Google Scholar Nahimana A, Aubry D, Breton CS, Majjigapu SR, Sordat B, Vogel P, et al. The anti-lymphoma activity...