Endocrinemonoclonalantibodies are drugs used for treating bone disorders. These antibodies treathypophosphatemiacaused due to excess activity of a phosphaturic hormone fibroblast growth factor-23 (FGF23). FGF23 is a bone-derived hormone that regulates the phosphate level in the body. Phosphate is respo...
COVID-19 monoclonal antibodies are protein molecules produced in the laboratory using DNArecombinanttechnology. Most of the COVID-9 monoclonal antibodies used for prevention (prophylaxis) or treatment of COVID-19 are designed to specifically bind to the viral spike protein, and prevent viral attachmen...
Monoclonal antibody INNs comprise a mab suffix preceded by a substem indicating the antibody type, e.g., chimeric (-xi-), humanized (-zu-), or human (-u-). The WHO publishes INN definitions that specify how new monoclonal antibody therapeutics are categorized and adapts the definitions to ...
The rapidly expanding list of monoclonal antibodies (MAbs) to human cell surface antigens provides reagents to probe the biology of malignant melanoma and ... Various - 《Saudi Journal of Biological Sciences》 被引量: 0发表: 2015年 Soak It Up at the Lesbian Bathhouse: A New Generation of Dy...
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New insights into anti-HER-2 receptor monoclonal antibody research Abnormalities in the expression, structure, or activity of proto-oncogene products contribute to the development and maintenance of the malignant phenotype... R Kumar,M Mandal,R Vadlamudi - 《Seminars in Oncology》 被引量: 58发表:...
ADCs are expected to be one of the most important areas of monoclonal antibody development in the next decade, especially in targeted therapies for oncology, an area where Ambrx has a strong internal pipeline. The company’s most advanced internally developed product is ARX788, a site-specific ...
“The federal government controls the distribution of monoclonal antibodies, and the regional infusion centers in Austin, El Paso, Fort Worth, San Antonio and The Woodlands have exhausted their supply of sotrovimab, the monoclonal antibody effective against the COVID-19 Omicron variant, due to the...
According to the trade publication SpaceNews, Bridenstine has been a big proponent of giving the private sector a larger role in space. The space agency is involved in all aspects of space exploration, as well as in Earth observation missions from space and in the development of new aerospace...
Over the past two decades, there has been an increase in the research and development and therapeutic application of monoclonal antibodies (mAbs). An application of pharmacokinetic (PK) and pharmacodynamic concepts that has likely contributed to the success of the pre-clinical and clinical drug ...