Chemotherapymodulating agents are a class of drugs used to treat asymptomatic or minimally symptomatic metastatic castrate-resistant (hormone-refractory)prostate cancer. The only drug that belongs to this class is “sipuleucel-T,” anautologous, personalized cellularimmunotherapy(a type of vaccine) created...
Two immunotherapy drugs for previously untreated CLL, obinutuzumab and ofatumumab (in combination with standard chemotherapy) Two molecularly targeted drugs for treatment-resistant or relapsed CLL, ibrutinib and idelalisib "These new therapies fill an enormous need for thousands of patients living with CLL...
Antineoplasticanthracyclines are a class of drugs used to treat various cancers, includingleukemia(acutelymphocyticleukemia and acute myeloid leukemia), lymphomas, cancers of the breast, stomach,uterus, ovary,bladder, andlungs, Hodgkin'slymphoma(cancer of the lymphatic system), and non-Hodgkin's lympho...
METHODS The proposed method (DrugEx) consists of a named entity recogniser (NER) to identify drugs and associated attributes, and relation extraction (RE) component to identify relations between them. For the NER, we explored deep learning-based approaches (i.e. Bi-LSTM-CRFs) with various ...
CHEMOTHERAPYDRUGS -- OverdosePHARMACEUTICAL industryConfusion due to similar looking or sounding drug names is a common problem that can result in potentially serious medication errors. Regulatory agencies and the pharmaceutical industry have recently made efforts to reduce this problem by reviewing new ...
Inducing DNA damage is known to be one of the mechanisms of cytotoxic chemotherapy agents for cancer such as cisplatin. The endogenous DNA damage response ... Q Shi,L Shen,B Dong,... - 《Cancer Letters》 被引量: 5发表: 2018年 An Integrated Guide and Control Strategy to Enhance the Prec...
Look-alike, sound-alike oncology medications. Confusing medication names and packaging may cause or contribute to potentially harmful medication errors. The names of several chemotherapy and supportive... Schulmeister,Lisa - 《Clinical Journal of Oncology Nursing》 被引量: 59发表: 2006年 ...
Cancer stem cells (CSCs) accounts for recurrence and resistance to chemotherapy in various tumors. Efficacy of chemotherapeutic drugs is limited by tumor s... Arthur, PeggyPatel, NilkumarSurapaneni, Sunil KumarMondal, ArindamGebeyehu, AragawBagde, ArvindKutlehria, ShalluNottingham, EbonySingh, Man...
There is an urgent need for new drugs to treat malaria, with broad therapeutic potential and novel modes of action, to widen the scope of treatment and to overcome emerging drug resistance. We describe the discovery of DDD107498, a compo... - 《Nature》 被引量: 176发表: 2015年 The Empir...
Chemotherapyassociated nausea or vomiting Stuttering Alcohol dependence Insomnia Psychosis or agitation related to Alzheimer’sdementia Posttraumaticstressdisorder (PTSD) Orphan designation: N-glycanase 1 (NGLY1) deficiency What Are Side Effects of Second Generation Antipsychotics?