Considering peptidergic drugs, many cytokines, enzymes, clotting factors registered for the use as therapeutic agents in specific conditions, they are main... Ilic, Spomenko,Drmic, Domagoj,Kolenc, Danijela,... - 《Gastroenterology》 被引量: 2发表: 2009年 Pentadecapeptide BPC 157 and the centra...
clotting is promoted and blood flow through vessels and valves is impeded. A stroke results when blood flow to regions of the brain is blocked. Aspirin inhibits enzymes in platelet membranes responsible for the formation of platelet aggregation factors, and thus reduces the risk ...
Nitric oxide (NO) has been shown to stimulate differentiation and increase the survival of ganglionic sympathetic neurons. The proportion of neuronal NOS-immunoreactive sympathetic preganglionic neurons is particularly high in newborn rats and decreases
Introduction Hypertension is one of the most important factors associated with development of several diseases such as heart failure, renal failure [1], coronary heart disease, atherosclerosis, myocardial infarction [2] and stroke [3]. Endothelial dysfunction, which results from nitric oxide (NO) ...
Background: Clotting factor (F) VIII is an independent risk factor for primary and recurrent venous thromboembolism (VTE). The causes for high plasma FVIII levels are not fully understood, but an involvement of genetic factors has been demonstrated. A multifunctional endocytic receptor, low-density...
The Effect of Demographic Factors and VKORC1 1639 G > A Genotypes on Estimated Warfarin Maintenance Dose in Iranian Patients Under Warfarin Therapy text>Warfarin is an anticoagulant that inhibits vitamin K-dependent clotting factors including factor (F) II, FVII, FIX and FX. Different factors can...
Note. The nomenclature of the blood coagulation factors is that recommended by the Task Force on Nomenclature of Blood Clotting Zymogens and Zymogen Intermediates. Publication History Issue published online: 3 MAR 2005 Article first published online: 3 MAR 2005 (Received September 29/November 27, 19...
Infants exposedin uteroto enzyme inducing AEDs may have a coagulopathy at birth due to decreased vitamin K-dependent clotting factors and this may be prevented by maternal supplementation with vitamin K1, 10–20 mg/day orally, for 2 weeks before delivery.28Infants at risk should be given phytona...
A method for the quantitative determination of vitamin K 1 (20) (VK), an essential cofactor in the carboxylation of clotting factors, is presented. The assay is based on gas chromatography/electron impact mass/spectrometry. The preparation of deuterium-labelled vitamin K 1 (20) for use as a...
Warfarin acts through the inhibition of vitamin K reductase in the vitamin K cycle, thereby preventing the activation of clotting factors II, VII, IX and X and proteins C, S and Z [ 2 , 3 ]. However, vitamin K 1 can be reduced through another pathway, and a high intake ...