Recent years have seen so-called natural killer T (NKT) cells emerge as important regulators of the immune response. The existence of NKT-cell subsets, and other types of T cell that resemble NKT cells, is an ongoing source of confusion in the literature
13 Interestingly, several types of tumor cells produce IL-6, and IL-6 has been proposed to act as an autocrine and paracrine growth factor for different types of neoplasms.14 However, IL-6 may be an effective antitumor agent because of its ability to enhance antitumor T-cell-mediated immune...
Journal of innate immunity (May 2015; 6: 377) "A new domain in the Toll/IL-1R domain-containing adaptor inducing interferon- factor protein amino terminus is important for tumor necrosis factor- receptor-associated factor 3 association, protein stabilization and interferon signaling." Author(s):...
The F4/80 antigen is expressed by a majority of mature macrophages and is one of the best markers for this population of cells. However, other cell types, such as peritoneal eosinophils, Langerhans cells, and some other dendritic cell subtypes, have been reported to...