This glycan polymer, interconnected by pentapeptide chains, is composed of repeating units of N-acetylglucosamine (NAG) and N-acetyl muramic acid (NAM) joined through a beta 1,4 linkage. In periods of growth and infection, PGN fragments shed by the bacterial cell are detected by pattern ...
A third and equally important member of this group is the disaccharide building block of the bacterial cell wall. The researchers describe the NMR structure of a synthesized fragment incorporating two of these disaacharides and their two pendant peptides, which cross-link the glycan strands in ...
A New Route to NAG-NAM Disaccharide, an Important Building Block for Peptidoglycan Oligomer Synthesispeptidoglycanmuropeptideoligosaccharidechitinbioseselective deacylationPeptidoglycan oligomers constitute precious tools for the biochemical and structural studies of enzymes involved in the bacterial cell wall ...
In addition, resistance of pathogenic microorganisms to antibiotics is an increasing problem. As part of a program to identify essential oils as alternative larvicidal and antimicrobial agents, the leaf, stem, and rhizome essential oils of several Zingiber species, obtained from wild-growing specimens...