Alcohol dependence and opioid use disorder:The recommended dose is naltrexone 380 mg delivered intramuscularly (IM) as a gluteal injection every 4 weeks or once a month, alternating buttocks for each subsequent. Comments: There is no data specifically addressing switching from buprenorphine or methadon...
Uses Side Effects Warnings & Precautions Interactions Overdose/Missed Dose Reviews (185) Uses What is naltrexone used for? Naltrexone is commonly used for the following conditions: To help people with an alcohol use disorder who have already stopped drinking maintain their ability to no longer dr...
VIVITROL For Opioid Use Disorder Advise patients that if they previously used opioids, they may be more sensitive to lower doses of opioids and at risk of accidental overdose should they use opioids when their next dose is due, if they miss a dose, or after VIVITROL treatment is discontinued...
Maximum dose: 1 tablet orally 2 times a day (morning and evening) Avoid Concomitant Use with CYP450 2B6 Inducers PrecautionsUS BOXED WARNING: SUICIDAL THOUGHTS AND BEHAVIORSSuicidality and Antidepressant Drugs: This drug is not approved for use in the treatment of major depressive disorder or ...
Suicidality and depression have been reported with naltrexone use in the treatment of opioid dependence, although causal relationship has not been established. Bupropion use carries a dose-related risk for seizures. Consider the patient’s risk factors for seizures before starting bupropion/naltrexone. ...
7, 8 Exclusion criteria included (1) DSM-IV diagnosis of major Axis-1 psychiatric disorder including any history of substance use disorder (including nicotine), (2) use of a psychoactive substance within the past 30 days, (3) history of serious medical conditions, (4) consumption of more ...
have risk factors for bipolar disorder. Prior to initiating CONTRAVE, screen patients for history of bipolar disorder and the presence of risk factors for bipolar disorder (eg, family history of bipolar disorder, suicide, or depression). CONTRAVE is not approved for use in treating bipolar ...
Background: Extended-release (XR) naltrexone can prevent relapse to opioid use disorder following detoxification. However, one of the barriers to initiating XR-naltrexone is the recommendation for a 7–10-day period of abstinence from opioids prior to the first dose. Objectives: The current study...
low blood sugar or low sodium; liver or kidney problems; high blood pressure; heart attack, heart problems, or stroke; eating disorder; drinking a lot of alcohol; prescription medicine or street drug abuse; are 65 or older; diabetes; pregnant or planning to become pregnant; or breastfeeding....
study on major depressive disorder where the authors randomized 12 patients to naltrexone 1 mg/day or placebo, there were borderline significant improvements in some clinical depression measures4. These results are part of the documentation in a patent application on the use of LDN in depression ...