Since naltrexone seems to disrupt the connection between alcohol-induced stimulation and further alcohol consumption, there may be a time-critical period between drinks necessary for alcoholics to benefit from its effects. These findings are consistent with clinical trial data that suggest a potential ...
Review: naltrexone reduces alcohol consumption (in short term) in patients with alcohol dependence. Evid Based Med. 2005;10:120.Srisurapanont, M. and Jarusuraisin, N. 2005. Review: Naltrexone Reduces Alcohol Consumption (in the Short-Term) in Patients with Alcohol Dependence. Evidence Based ...
When used in conjunction with behavior modification, naltrexone reportedly decreases alcohol craving, reduces alcohol consumption, decreases the number of drinking days, maintains abstinence from alcohol ingestion, and prevents, decreases, or ameliorates the severity of relapse....
consumption of opiates becomes pointless since effect of drug is neutralised. For decades alreadyNaltrexone pellet implant therapyis helping people in their fight against alcohol and drug dependence. Naltrexone treatment for alcoholism and drug addiction is actually an alternative therapy to methadone, ...
Naltrexone effects on alcohol consumption in a clinical laboratory paradigm: temporal effects of drinking. Psychophar- macology (Berl) 173: 32–40. findings have greatest relevance for the non-treatment- Anton RF, Moak DH, Latham PK (1996). The obsessive compulsive seeking population studied here...
- 《Alcoholism Clinical & Experimental Research》 被引量: 150发表: 2010年 Family history and antisocial traits moderate naltrexone's effects on heavy drinking in alcoholics. Naltrexone's (NAL) effects on alcohol consumption are generally modest, so identifying patients likely to benefit would improve...
reducing the amount of alcohol consumed than producing complete abstinence;1 reports6 from patients who continued to drink during therapy suggest that naltrexone may reduce the pleasure associated with drinking, possibly by blocking the effect of endorphins released as a result of alcohol consumption. ...
Opioid antagonists have been shown to reduce alcohol consumption by animals, and REVIA has been shown to reduce alcohol consumption in clinical studies. REVIA is not aversive therapy and does not cause a disulfiram-like reaction either as a result of opiate use or ethanol ingestion. ...
Secondary effectiveness measures included time to first drink, amount of alcohol consumption, intensity of craving, severity of alcoholism problems, and liver enzymes. Thirty-three (38%) placebo patients and 28 (33%) naltrexone patients discontinued the study. At endpoint, 62% of the patients in...
and also the risk of relapse into excessive alcohol consumption and dependence. However, these effects are not maintained after 8–10 weeks, unless psychosocial therapeutic techniques and support are also in place. The combination of naltrexone and acamprosate together with behavioral interventions seems...