If you have risk factors for MASLD you may need a diagnostic evaluation so you and your medical team will know if you are developing fatty liver. And if you have started to develop some of the effects, then you may need a diagnostic workup to identify the cause of your symptoms. Some ...
An important reason why some phase 2 trials failed to show sufficient efficacy is because they were either underpowered in terms of sample size or too short in duration to show some effects. This is a slowly evolving disease, and it likely takes a long time for fibrosis to disappear. It's...
Histological assessment of nonalcoholic fatty liver disease (NAFLD) is essential for clinical practice as it outlines diagnosis and lays the foundation of medical care. This Perspective summarizes the advancements in digital histology and discusses current and future applications in NAFLD. ...
In this study, we aimed to investigate how obesity in adolescents and non-alcoholic liver disease (NAFLD) within the obese group affect TL and the clinical significance of the human telomerase reverse transcriptase (hTERT) gene MNS16A VNTR variant in terms of NAFLD. Adolescents with exogenous ...
Also, some studies showed that high doses of vitamin E could be dangerous for people with other medical conditions as well as FLD. Coffee. Caffeinated coffee has long been thought to be good for the liver and linked to slowing down liver scarring in various liver diseases. It's not clear...
We performed subgroup analyses based on included covariates and identified potential effect modifiers using interaction terms in our multivariate logistic regression models. The statistical significance of these interaction terms (p < 0.05) indicated the presence of effect modification. Finally, we ...
Beer L, Mattson CL, Bradley H, Skarbinski J, Medical Monitoring P. Understanding cross-sectional racial, ethnic, and gender disparities in antiretroviral use and viral suppression among HIV patients in the United States. Medicine (Baltimore). 2016;95(13):e 3171. Article CAS Google Scholar Gan...
In terms of other secondary efficacy indicators, including lipid, blood glucose and insulin levels, inflammatory cytokines, and obesity parameter, there were no significant differences between the placebo and ZSP1601 treatment groups at the end of treatment, compared to baseline. Discussion This ...
Department of Endocrinology and Diabetology, Medical Faculty and University Hospital, Heinrich Heine University, Düsseldorf, Germany Michael Roden Institute for Clinical Diabetology, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research at Heinrich-Heine University, Düsseldorf, Germany ...
In terms of mechanism, puerarin treatment inhibited the activity of CYP2E1 to maintain alcohol metabolic homeostasis and reduce oxidative stress [96,97]. Other studies investigated the effect of puerarin on CCl4-induced liver injury in mice. The results indicated that the hepatoprotective effect of ...