dokonale krásně jsi vystavěn.5 Tvá prkna vyrobili z hermonských [a] cypřišů,na tvůj stěžeň vzali cedr z Libanonu,6 tvá vesla zhotovili z bášanských dubů,z kyperských jedlí a slonoviny udělali palubu.7 Plachtu máš z pestrého kmentu z Egypta,...
Beyond mitochondria, other signatures contributed to the molecular perturbations of human sarcopenic muscle. In particular, ribosome and translation ontologies were overrepresented in the genes downregulated in sarcopenia (Fig.2a; Supplementary Fig.2g). Altered muscle protein synthesis has been widely associa...
Throughout their life cells are exposed to a number of harmful conditions considered detrimental for their survival. These conditions termed “Aging Stimuli” emanate from either the changing environmental state (e.g., exposure to chemical agents and general stress) or genetic influences (e.g., ge...
translation, protein secretion, and carbohydrate metabolic processes were downregulated in chondrocytes II. On the other hand, biological processes such as angiogenesis, cell adhesion, and cell death were upregulated in chondrocytes II
Thus, this comprehensive review provides updated, critically revised information on the potential therapeutic effects of boosting NAD+ metabolism in animal models of cardiovascular diseases and its potential translation into clinical practice. In particular, we mainly focus on the role of NAD+-increasing...