Aldehyde dehydrogenase from Pseudomonas testosteroni was purified to homogeneity. The enzyme has a pH optimum of 8.2, uses a wide range of aldehydes as substrates and cationic dyes (Wurster's blue, phenazine methosulphate and thionine), but not anionic dyes (ferricyanide and 2.6-dichloroindophenol),...
Aldehyde dehydrogenase from Pseudomonas testosteroni was purified to homogeneity. The enzyme has a pH optimum of 8.2, uses a wide range of aldehydes as substrates and cationic dyes (Wurster's blue, phenazine methosulphate and thionine), but not anionic dyes (ferricyanide and 2.6-dichloroindophenol),...
NA D+-i ndependent aldehyde oxid ase catalyzes cofactor balanced 3-hydroxypropionic acid production in Klebsiella pneumoniae[J]. Biotechnology Letters,2014,36(11): 2215-2221.Su, M., Li, Y., Ge, X. and Tian, P. (2015). 3-Hydroxypropionaldehyde-specific aldehyde dehydrogenase from Bacillus ...
The aldehyde dehydrogenase (ALDH) superfamily contains NAD(P) + -dependent enzymes that catalyze the oxidation of aldehydes to their corresponding carboxylic acids. Nineteen ALDH genes have been identified in the human genome. Mutations in these genes leading to enzyme inactivation are the molecular ba...
Among abundant proteins with a high number of peptide spectrum matches (> 300), we noticed that the NAD(P)-dependent enzymes, retinal dehydrogenase (ALDH1A1), aldehyde dehydrogenase-dimeric NADP-preferring (ALDH3A1), aldo-keto reductase family 1 member C3 and B10 (AKR1C3/B10), and fatty ...
Structural shifts of aldehyde dehydrogenase enzymes were instrumental for the early evolution of retinoid- dependent axial patterning in metazoans. Proc Natl Acad Sci. 108(1), 226–231 (2011). 35. Perez-Miller, S. J. & Hurley, T. D. Coenzyme isomerization is integral to catalysis in ...
Long-chain alcohol and aldehyde dehydrogenase activities in Acinetobacter calcoaceticus strain HO1-N Three alcohol dehydrogenases have been identified in Acinetobacter calcoaceticus sp. strain HO1-N: an NAD-dependent enzyme and two NADP-dependent enzymes. ... MGA Fox,FM Dickinson,C Ratledge - 《Micr...
one system being a NAD-dependent dehydrogenase and another being a NAD-independent dehydrogenase. A disadvantage of this procedure is that the NAD-independent enzymes necessary for a major proportion of the substances to be investigated in clinical diagnostics are not commercially available, in contrast...
The 2′,3′-dialdehyde nicotinamide ribose derivatives of NAD (oNAD) and NADH (oNADH) have been prepared enzymatically from the corresponding 2′,3′-dialdehyde analogs of NADP and NADPH. Pig heart NAD-dependent isocitrate dehydrogenase requires NAD as coenzyme but binds NADPH, as well as NAD...
Nicotinamide adenine dinucleotide (NAD+) is a critical metabolite that acts as a cofactor in energy metabolism, and serves as a cosubstrate for non-redox NAD+-dependent enzymes, including sirtuins, CD38 and poly(ADP-ribose) polymerases. NAD+ metabolism can regulate functionality attributes of innate...