Morley, Kirsten C et al. “N-acetyl cysteine in the treatment of alcohol use disorder in patients with liver disease: Rationale for further research.” Expert opinion on investigational drugs vol. 27,8 (2018): 6...
N-乙酰半胱氨酸(NAC)作为药物已经有近60年的运用史(早在1963年9月被批准上市),早期用于NAC也是解毒扑热息痛(对酰氨基酚p-acetaminophen)中毒的方法之一。 扑热息痛代谢为有毒的化合物后会导致肝脏的谷胱甘肽储备流失,进而损害肝脏。 扑热息痛摄入过量或与酒精一起摄入时,造成的谷胱甘肽流失可以致命。 NAC目前在...
英文名称:N-Acetyl Cysteine,NAC 作用机制与循证 N-乙酰半胱氨酸(NAC)是半胱氨酸的特殊修饰形式。NAC具有抗氧化活性,并能促进肝脏合成谷胱甘肽抗氧化酶、维持肝功能、肝解毒等;NAC支持肺功能作用明显,可溶解粘液、辅助治疗慢性支气管炎等。...
Morley, Kirsten C et al. “N-acetyl cysteine in the treatment of alcohol use disorder in patients with liver disease: Rationale for further research.” Expert opinion on investigational drugs vol. 27,8 (2018): 667-675. doi:10.1080/13543784.2018.1501471 https://www.tandfonline.com/doi/full/...
N-acetylcysteine (NAC), a form of the amino acid cysteine, is widely used in emergency medicine to treat individuals who overdose on acetaminophen or paracetamol. Placebo-controlled studies have investigated the effectiveness of NAC as a treatment of major depressive disorder, bipolar disorder, ...
N-Acetylcysteine is the supplement form of Cysteine, an amino acid. Amino acids form the building blocks of proteins in the body. Cysteine is also important for the production of glutathione (the body’s most powerful antioxidant). 14 NAC Benefits ...
N-acetyl cysteine (NAC), a derivative of the amino acid L-cysteine,is a potent antioxidant that regenerates glutathione in the cell . In this role,NAC protects liver cellsby decreasing oxidation. Cysteine appears to decline in people with HIV who have low CD4+ cell counts and in those with...
抗氧化剂NAC(N-乙酰半胱氨酸) 英文名:N-acetyl-L-cysteine 规格:2g 产地:国产|进口 编号:YT305 本品是一种常用的抗氧化剂。有报道可以抑制 神经细胞 的凋亡,但可以诱导平滑肌细胞凋亡。可以抑制 hiv 复制。溶解于水
之所以做乙酰化的的修饰,是为了提升口服吸收率。关于NAC的详细科普请参考下文(2000字+):N-乙酰半胱...
NAC 即N-acetyl-L-cysteine,也称LNAC,中文名为N-乙酰半胱氨酸,是一种常用的抗氧化剂。有报道可以抑制神经细胞的凋亡,但可以诱导平滑肌细胞凋亡。可以抑制HIV 复制。 NAC 为接近白色的粉末,分子量163.19,分子式为C5H9NO3S,纯度大于99%。溶解于水,加热后在水中的溶解度可以达到100mg/ml。