3. Mechanism for the Reduction of Aldehydes and Ketones With NaBH4 The mechanism for these reductions follows the very common two-step addition-protonation pattern often found in reactions of aldehydes and keto
ngofNaBH4withtheethanolsolutionofCeC l3‟7H20.Thereforeitishighlyprobableth attheactualreducingspeciesisnotBH4一, butthe/ns/tuderivedalkoxyborohydrid e.ApossiblereactionmechanismWaspropo sed.Keywords:NaBH4,Reduction,Catalys is,Esters,Alcohols声明本学位论文是我在导师的指导下取得 的研究成果,尽我所知,在本...
This mechanism is for a LiAlH4 reduction. The mechanism for a NaBH4 reduction is the same except methanol is the proton source used in the second step. 1) Nucleophilic attack by the hydride anion 2) The alkoxide is protonated Going from Reactants to Products Simplified Properties of hydrid...
So I thought let’s look at the mechanism of ester with LiAlH4, which goes as followed: What I see is that there are two reduction processes to receive the final product. While the reduction of an ketone only has one. Does this explain the difference in reactivity? So why isn’t it ...
A possible reaction mechanism is proposed based on the experimental and computational findings, including XPS analysis, kinetic studies, acidity measurements, and density functional theory (DFT) calculations. The high effectiveness of the proposed system is attributed to (1) the strong metal support ...