Na+/H+ exchangerNHXOne important mechanism plants use to cope with salinity is keeping the cytosolic Na+ concentration low by sequestering Na+ in vacuoles, a process facilitated by Na+/H+ exchangers (NHX). There are eight NHX genes (NHX1 through NHX8) identified and characterized in ...
植物 Na+,K+/H+ 反向 转运体是位于细胞膜结构上的跨膜反向转运蛋白,介导 Na+,K+ 与质子(H+)的跨膜反向转运,影响胞内 pH 的动态平衡.研究表 明,NHX 缺失造成细胞 pH 失衡的同时,将影响囊泡运输,从而对生长发育产生不利影响.主要对植物 NHX 在 pH 调节,囊泡运 输中的功能进展进行了概述,并对其关系...
迄今, 离子区域化酶类基因, 尤其是Na+/H+逆向转运蛋白基因SOS(salt overly sensitive)的克隆和功能分析, 是植物耐盐分子机制研究的热点。Gaxiola等[20]从拟南芥克隆到一个液泡膜Na+/H+逆向转运蛋白基因AtNHX1 (Na+/H+exchanger, NHX), 发现该基因与拟南芥H+-PPase基因AVP1(Arabidopis thaliana vacuolar-type...
Na+/H+ exchanger catalyzes the countertransport of Na+ and H+ across membranes. We isolated a rice cDNA clone the deduced amino acid sequence of which had homology with a putative Na+/H+ exchanger in Saccharomyces cerevisiae, NHX1. The sequence contains 2330 bp with an open reading frame ...
Chapter 6 - Na+/H+ antiporter (NHX) and salt stress tolerance Na+/H+ Exchanger (NHE) proteins mediate cellular and systemic homeostasis of sodium and acid and may be the major sodium uptake method for fishes. We clone... H Sharma,A Sharma,S Sidhu,... - Elsevier Inc. 被引量: 0发表...
Na[sup +]/H[sup +] exchangers are involved in cell volume regulation, fluid secretion and absorption, and pH homeostasis. NHX-2 is a Caenorhabditis elegans Na[sup +]/H[sup +] exchanger expressed exclusively at the apical membrane of intestinal epithelial cells. The inactivation of various int...
KLH-conjugated synthetic peptide derived from Arabidopsis thaliana NHX protein UniProt: Q68KI4, TAIR: At5g27150; chosen peptide is perfectly confirmed in AtNHX1 UniProt: Q0WVZ5, partially in AtNHX2, UniProt: Q56XP4, and not conserved in AtNHX3, UniProt: Q84WG1 and AtNHX4, UniProt:Q8...
knockout mutant of AtNHX1 (nhx1), and a 'rescued' line (NHX1::nhx1) were exposed to both short (12 h and 48 h) and long (one and two weeks) durations of a non-lethal salt stress to identify key gene transcripts associated with the salt response that are influenced by AtNHX1. ...
Intracellular pathways mediating Na+/H+ exchange activation by platelet-derived growth factor in rat hepatic stellate cells. The Na+/H+ exchanger is the main intracellular pH regulator in hepatic stellate cells (HSCs), and its activity is increased by platelet-derived growth fact... SA Di,E Be...
2.4 离子转运载体与SOS1协同调节离子稳态平衡 盐胁迫下,植物通过激活多种信号通路和离子 转运体来调控离子动态平衡[69, 96],离子转运体如 NHX,AKT1 和 HKT 与 SOS1 协同调节离子稳态平衡. 当植物将胞质 Na+ 水平保持在 10-50 mmol/L 时,首 先是通过质膜 H+‑ATPase 产生质子动力驱动 SOS1, 将胞质中 ...