Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine Transition-state destabilization reveals how human DNA polymeraseβproceeds across the chemically unstable lesion N7-me thylguanine. Koag,M.-C. Nucleic ... Koag,MC,...
& Hori, H. N 7-methylguanine at position 46 (m7G46) in tRNA from thermus thermophilus is required for cell viability at high temperatures through a tRNA modification network. Nucleic Acids Res. 38, 942–957 (2010). CAS PubMed Google Scholar White, J. et al. Bud23 methylates G1575 of...
(7)-)-methyltransferase that is a part of the methyltransferase superfamily. METTL1 displays high sequence similarity to yeast ORF YDL201w and can be inactivated by phosphorylation. METTL1 protein has a conserved S-adenosylmethionine-binding motif and ccatalyzes the formation of N(7)-methylguanine ...
Using a competitive repair assay, 407 samples of peripheral blood leucocyte DNA from randomly selected subjects in 17 populations were tested for the presence of the adduct O6-methylguanine. With a limit of assay sensitivity of 0.05 fmol... N Listed - 《Carcinogenesis》 被引量: 73发表: 1994年...
(N7, O6) of the other is the dominant association pattern in the solid-state structures of two hydrates of 9-ethylguanine (9-EtGH), and in adducts of 9-methylguanine (9-MeGH) with the Zn compounds [ZnCl2(H2O)(9-MeGH-N7)]*(9-MeGH) as well as [ZnCl2(H2O)(9-MeA-N7)]*2(9-...
Synonyms:Aniline, N,N-dimethyl-;Benzenamine,N,N-dimethyl-;N,N-dimethyl-Benzenamine;N,N-Dimethylbenzeneamine;N,N-Dimethyl-N-phenylamine;N,N-Dimethylphenylamine;N,N-DIMETHYLACETATE;N-ACETYLDIMETHYLAMINE CAS:121-69-7 MF:C8H11N MW:121.18
Chemical Name6H-Purin-6-one,2-amino-1,7-dihydro-1,7-dimethyl- CAS No.26758-00-9 Molecular FormulaC7H9N5O Molecular Weight179.18 PSA79.46000 PubChemID13988705 Synonyms1,7-Dimethylguanin; 1,7-Dimethylguanine; 2-Amino-1,7-dimethyl-1,7-dihydro-6H-purin-6-one; View More26758...
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Ab initio quantum-chemical calculations have been carried out to investigate the correlation between N1−H1 deprotonation energy and base pairing of modified guanines (neutral 8-oxoguanine (8OG) and monocationic 7,9-dimethylguanineH+ (DMG)) and dicationic platinated guanines. The calculated intrin...
The tris(nucleobase) complex [Pt(NH3)(Hmgua-N7)3]2+1 (Hmgua = 9-methylguanine) has been synthesised and crystallised as the nitrate (1a) and a mixed perchlorate, chloride salt (1b). In the cation of 1a the three bases are oriented head–tail–head, as in one of the two crystallo...