N1,N11-Diethylnorspermine tetrahydrochloride (DENSPM tetrahydrochloride) 可有效诱导 SSAT (亚精胺/精胺N1-乙酰转移酶) mRNA,并有效稳定 SSAT 酶活性。 名称 中文名N1,N11-二乙基去甲精胺四盐酸盐 英文名N1,N1'-1,3-Propanediylbis(N3-ethyl-1,3-propanediamine) tetrahydrochloride ...
N1,N11-二乙基去甲精胺四盐酸盐名称 中文名N1,N11-二乙基去甲精胺四盐酸盐 英文名N1,N11-Diethylnorspermine tetrahydrochloride,N,N'-bis[3-(Ethylamino)propyl]-1,3-propanediaminetetrahydrochloride 英文别名更多 N1,N11-二乙基去甲精胺四盐酸盐生物活性 ...
N1,N11-Diethylnorspermine tetrahydrochloride InChi 编码: 1S/C13H32N4.4ClH/c1-3-14-8-5-10-16-12-7-13-17-11-6-9-15-4-2;;;/h14-17H,3-13H2,1-2H3;4*1H N1,N11-Diethylnorspermine tetrahydrochloride InChiKey 编码: LAWBSOKBIROCQP-UHFFFAOYSA-N chem960为您提供 10 家 N1,N11-Diet...
N1,N11-Diethylnorspermine tetrahydrochloride (DENSPM tetrahydrochloride) 可有效诱导 SSAT (亚精胺/精胺N1-乙酰转移酶) mRNA,并有效稳定 SSAT 酶活性。 Product Describtion: N1,N11-Diethylnorspermine tetrahydrochloride (DENSPM tetrahydrochloride) potently induces SSAT (spermidine/spermine N1-acetyltransferase) mR...
N1,N11-Diethylnorspermine4HCldenspmn(sup1),n(sup11)-bis(ethyl)norsperminen(1),n(11)-diethylnorsperminen(sup1),n(sup11)-diethylnorspermineN,N'-BIS[3-(ETHYLAMINO)PROPYL]-1,3-PROPANEDIAMINE TETRAHYDROCHLORIDEN',N''-DIETHYLNORSPERMINE TETRAHYDROCHLORIDEn,n’-bis(3-(ethylamino)propyl)-3-pro...
N1, N11‐diethyl[6‐14C]norspermineCI‐1006diethyl[2‐14C]malonateanticancer agentN 1, N 11 Diethylnorspermine, CI-1006, a potential new anticancer drug, was synthesized with a carbon-14 located at the central carbon of the molecule. Condensation of N-(2,4,6-trimethylbenzenesulfon...
The pharmacokinetics and metabolism of N1,N11-diethylnorspermine (DENSPM) is described. When administered to dogs as an intravenous bolus, DENSPM was shown to have a plasma half-life of 72.8 +/- 11.8 min, with an early distribution phase half-life of approximately 4 min and an apparent vol...
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The objectives of this study were to determine the dose limiting toxicity (DLT) and other major toxicities, the maximum tolerated dose (MTD) and the human pharmacokinetics of N 1 N 11 diethylnorspermine (DENSPM), a new polyamine analog which in experimental systems inhibits the biosynthesis of...
Antitumor activity of the polyamine analog N1,N11-diethylnorspermine against human prostate carcinoma cellsdoi:10.1002/1097-0045(20000901)44:4<313::aid-pros8>3.0.co;2-dprostate cancerpolyamine analogspolyaminesspermidine/spermine N1-acetyltransferase...