Shibata K, Matsuo H. Changes in the ratio of Nl-methyl-2-pyridone-5- carboxamide to Nl-methyl-4-pyridone-3-carboxamide excretion following a large amount of Nl-methylnicotinamide injection in rats. Agric Biol Chem 1989;53:1161-1162.
Although purified xanthine oxidase had previously been shown to be capable of catalyzing the formation of N 1-methyl-2-pyridone-5-carboxamide (2-pyridone) at pH values above 8.0, this is the first documentation of such catalysis in vivo. The aldehyde oxidases of both man and the rat are ...
1-methyl-4-oxo-pyridine-3-carboxamide 英文别名: N-Methyl-4-pyridone-5-carboxamide;N-Methyl-4-pyridone-3-carboxaMide;N1-Methyl-4-pyridone-5-carboxamide;1-methyl-4-oxo-pyridine-3-carboxamide;1,4-Dihydro-1-methyl-4-oxonicotinamide;3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-4-oxo-;1-Methyl-...
When a large amount of nicotinamide (500 mg per kg body weight) was intraperitoneally injected into rats, the ratio of A^-methyl-4-pyridone-3-carboxamide (4-py) to N1-methyl-2-pyridone-5- carboxamide (2-py) excretion steeply decreased until 24 hr after injection, then this excretion ...
(4PY), N-methyl nicotinic acid (NMNA) or N-methyl nicotinamide (NMND), in a sample taken from an individual, wherein the method does not comprise assessing hippurate and/or 4-hydroxyhippurate alone, and wherein the method does not comprise assessing N-methyl-2-pyridone-5-carboxamide ...
The excretion of N1-methyl-2-pyridone-5-carboxylic acid and related compounds in human subjects after oral administration of nicotinic acid, trigonelline and N1-methyl-2-pyridone-5-carboxylic acid. Adv Exp Med Biol 1991;294:475-9.Yuyama, S., and Suzuki, T. (1991). The excretion of N1-...
Shibata K, Kawada T, Iwai K (1988) Simultaneous micro-determination of nicotinamide and its major metabolites, N 1-methyl-2-pyridone-5-carboxamide and N 1-methyl-4-pyridone-3-carboxamide, by high-performance liquid chromatography. J Chromatogr 424(1):23–28...
Inamadugu J K,Damaramadugu R,Mullangi R et al.Simultaneous Determination of Niacin and Its Metabolites-Nicotinamide,Nicotinuric Acid and N-Methyl-2-Pyridone-5-Carboxamide-in Human Plasma by LC-MS/MS and Its Application to a HumanPharmacokinetic Study.Biomedical Chromatography. 2010...
The gas phase catalytic methylation of 4-hydroxypyridine in the presence of the ZnAl2O4 catalyst was performed in a continuous process at atmospheric pressure in the temperature range of 240–360 °C. A mixture of O- and N-alkylated products, namely 4-methoxypyridine and N-methyl-4-pyridone ...
Therefore, the ratio of N1-methyl-2-pyridone-5-carboxamide and N1-methyl-4-pyridone-3-carboxamide to N1-methylnicotinamide excretion might be a more useful index for assessing the protein status than as an index for assessing the niacin status in rats and humans....