Israel M, Modest EJ (1977) N-Trifluoroacetyladriamy- cin-14-alkanoates and therapeutic compositions containing same. U.S. Patent No. 4,035,566, July 12Israel M, Modest EJ (1977) N -Trifluoroacetyladriamycin-14-alkanoates and therapeutic compositions containing same. U. S. Patent No. 4...
N-trifluoroacetyladriamycin-14-O-hemiadipate英文别名: Ad143;Nsc336379;Aids004411;Aids-004411;N-trifluoroacetyladriamycin-14-O-hemiadipate;Hexanedioic acid, 1-[2-[1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-...
英文名称: N-trifluoroacetyladriamycin-14-O-hemiadipate 英文同义词: N-trifluoroacetyladriamycin-14-O-hemiadipate;Ad143;Aids004411;Aids-004411;Nsc336379;Hexanedioic acid, 1-[2-[1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amin...
A'-Trifluoroacetyladriamycin-14-O-hemiglutarate and hemiadipate and therapeutic combinations containing same - Israel, Potti - 1981Israel, M., and Potti, P. G. N-Trifluoroacetyladriamycin-14-O-hemiglutarateand hemiadipate and therapeutic combinations containing same. U.S. Patent No. 4,299,822...
N-TRIFLUOROACETYLADRIAMYCIN-14-O-HEMIGLUTARATE AND HEMIADIPATE AND THERAPEUTIC COMPOSITIONS CONTAINING THE SAMEN-Trifluoroacetyladriamycin-14-O-hemiglutarate and -hemiadipate having antitumor activity and low toxicity are soluble in water at a physiological pH ranging from 7.2 to 7.5....
N-TRIFLUOROACETYLADRIAMYCIN-14-O-HEMIGLUTARATE AND HEMIADIPATE AND THERAPEUTIC COMPOSITIONS CONTAINING THE SAMEN-Trifluoroacetyladriamycin-14-O-hemiglutarate and -hemiadipate having antitumor activity and low toxicity are soluble in water at a physiological pH ranging from 7.2 to 7.5....
Garnick, MB, Griffin, JD, Sack, MJ, Blum, RH, Israel, M, Frei, E Phase II evaluation of N-trifluoroacetyladriamycin-14-valerate (AD-32). In: Muggia, FM, Young, CW, Carter, SK eds. (1982) Anthracycline antibiotics in cancer therapy. Martinus Nijhoff, The Haguepp. 451...
The interaction of adriamycin (ADR) and N-Trifluoroacetyladriamycin-14-valerate (AD 32) with cardiolipin (CL)-containing multilamellar vesicles was studied by high-sensitivity differential scanning calorimetry, using liposomes formed from either dipalmitoylphosphatidylcholine (DPPC) or dipalmitoyl...
We have performed a series of experiments using the chick embryo to investigate and compare the toxic and teratogenic effects of doxorubicin (DX) and its new analog N-trifluoroacetyladriamycin-4-valerate (AD-32). DX and AD-32, dissolved in 1:1 emulphor/ethanol and diluted to 1:4 with ...
Pharmacologic studies with radiolabeled N-trifluoroacetyladriamycin-14-valerate (AD 32)In connection with pharmacologic studies with AD 32, isotopically-labeled drug prepared from 1-[14C]-trifluoroacetic anhydride and adriamycin-14-valerate was used to determine murine serum and urine levels of ...