is used to modulate inflammation. This analysis revealed that Bay-117082 efficiently reduced total protein concentration, myeloperoxidase activity, and inflammatory cytokines in BALF. Moreover, Bay-117082 inhibited the formation of NETs, which in turn prevented the activation of the pore-forming protein...
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis GSDMD palmitoylation is an important and highly regulated checkpoint for pyroptosis, which serves as a crucial nexus between GSDMD cleavage and pore formation... A Balasubramanian,AY Hsu,L Ghimire,...