No N-deacetylation occurs on the ... Y Fan,T Saito,A Isogai - 《Biomacromolecules》 被引量: 270发表: 2008年 Preparation and physico-chemical characterization of chitin and chitosan from the pens of the squid species, and Mild alkaline deacetylation with various time periods was employed in ...
chitinaseschitobiosidedeacetylationnitrophenylselectivedifferentiate CarbohydrateResearch316(1999)173–178 SelectiveN-deacetylationofp-nitrophenyl N,N%-diacetyl-b-chitobiosideanditsusetodifferentiate theactionoftwotypesofchitinases KenTokuyasu a, *,HiroshiOno a ,YukiKitagawa b ,MayumiOhnishi-Kameyama a , Kiyosh...
(C5epimerizationandO-sulfonation),canimpacttheactionoftheseenzymesand,thus,thecontentanddistributionofiduronicacidandO-sulfogroups.Inthisstudy,wecontroltheN-deacetylationofheparosantoproduceabioengineeredheparinwithanN-acetyl/N-sulforatioandmolecularweightthatissimilartoanimal-sourcedpharmaceuticalheparin.Thestructural...
Guinea pigs also exhibited the highest renal cytosolic N-deacetylase activity and the lowest N-acetylase activity. The ratios of N-deacetylation to N-acetylation in guinea pigs, BALB/c mice, B6C3F1 mice, hamsters, Fischer 344 rats, and Sprague-Dawley rats were 4.57, 0.16, 0.14, 0.04, 0.03...
Peptides containing Nε-thioacetyl-lysine and Nε-acetyl-lysine were evaluated for their de(thio)acetylation catalyzed by human HDAC8 and SIRT1, two distinct protein deacetylases. Nε-Thioacetyl-lysine was found to be a mimic of Nε-acetyl-lysine for HDAC8-catalyzed reaction, but to confer...
N-terminal Region, C-terminal Region, Nuclear Export Signal, and Deacetylation Activity of Histone Deacetylase-3 Are Essential for the Viability of the DT4... (2000) N-terminal region, C-terminal region, nuclear export signal, and deacetylation activity of histone deacetylase-3 are essential for...
n-Butylmalonic acid was a slow-binding inhibitor of acylase I and inhibited the deacetylation of NAC with a Ki of 192 +/- 27 microM. These results show that acylase I catalyzes the deacetylation of NAC. The acylase I-catalyzed deacetylation of a range of S-alkyl-N-acetyl-L-cysteines, ...
N-acetylcysteine (NAC), an antioxidant, attenuated premature senescence and decreased renal fibrosis, and its effects were dependent on sirtuin1 (SIRT1) activation and p53 deacetylation. These results indicate that cisplatin can induce premature renal senescence, which is associated with the development...
Herein two highly N-deacetylated HAs, dHA-6 and dHA-10 were generated via the NH2NH2-HIO3 procedure. Their molecular weights were estimated to be 24 and 16 kDa by high performance gel-permeation chromatography (HPGPC), and the N-deacetylation degrees were 79.4 % and 93 % respectively, as ...
1) N-deacetylation N-脱乙酰反应2) deacetylation [diə,siti'leiʃən] 脱乙酰反应 1. The kinetics of heterogeneous deacetylation of chitin in alkaline solution under microwave irradiation in sealed and opening container were investigated in this paper. 比较了微波场中密闭式及开放式条件下,...