Molecular cloning of a novel human gene encoding histone acetyltransferase-like protein involved in transcriptional activation of hTERT Biochem. Biophys. Res. Commun., 311 (2003), pp. 506-513 View in ScopusGoogle Scholar [22] C.C. de Oliveira Mann, P.J. Kranzusch cGAS conducts micronuclei DN...
Although genomic factors seem to be in part implicated in such an impairment of melatonin synthesis, as genetic variants that lead to reduction of AANAT activities were found in a small proportion of ASD patients, the connection among miR-451, 14-3-3 protein, and melatonin production has...
The ngs1G696L mutant could not grow on GlcNAc like the ngs1 deletion mutant (Fig. 4b), and was unable to express NAG1 in response to GlcNAc (Fig. 4c). In addition, cells carrying the V686A mutation showed impaired induction of NAG1. The protein levels of both ngs1G696L and ngs1...
(Lys-C and Arg-C like digestion with trypsin, respectively) allowing increased coverage of the N-terminome. Collectively, we identified 1480 non-redundant Nt-peptides (Supplementary Fig.4B) considering only those covering the first or second amino acid of annotated protein sequences retrieved ...
Puromycin, an aminonucleoside antibiotic, is a potent inhibitor of protein translation in both eukaryotic and prokaryotic organisms. The gene encoding resistance to puromycin, puromycin N-acetyltransferase (pac), was isolated from Streptomyces alboniger9 and first used as a dominant selection marker for...
(CRISPR)-CRISPR-associated protein 9 had no obvious effect on larval and pupal development.However,the mutant mosquitoes exhibited a roughened ex-oskeletal surface,darker cuticles,and color pattern changes suggesting that Ae-aaNAT1 plays a role in development of the morphology and pigmentation of ...
(PDB 3TE4)60, the binding surface for the adenosine 3-phosphate 5-pyrophosphate moiety of CoA-SH is blocked by protein-protein interactions in the AgmNAT structure, but the rest of the active site is open. The splaying of β-strand four and five, a conserved structural feature in GNAT ...
N-acetylation of pANS by liver homogenates was measured in the presence of apocynin following preincubation of the appro- priately diluted S9 fractions (9.60 μg protein) with either apocynin (0.49 mM, 0, 5 or 15 min) or AcCoA (0.20 mM, 5 or 15 min). Varying ...
It has been shown that gene expression of the rate-limiting enzyme in the melatonin synthesis arylalkylamine N-acetyltransferase (Aa-Nat), circadian clock gene Period1, and mitogen-activated protein kinase (MAPK) phosphtase-1 (MKP-1), is controlled mainly by a norepinephrine-beta-adrenergic ...
wherein said polypeptide has glyphosate-N-acetyltransferase activity, wherein percent identity is calculated using ClustalW analysis (version W 1.8) using default parameters: Gap Open penalty of 10, gap extension penalty of 0.10, protein weight matrix: gonnet series; DNA weight matrix: IUB; toggle...