N-Acetylcysteine amide N-乙酰半胱氨酸酰胺对用多柔比星(DOX)处理的H9c2细胞的生存率没有明显影响,浓度低于1 mM,但在10-20 mM时会导致显著的细胞毒性。N-乙酰半胱氨酸酰胺 N-Acetylcysteine amide(750 μM)可以降低DOX诱导的活性氧(ROS)水平和脂质过氧化,并恢复谷胱甘肽(GSH)/氧化谷胱甘肽(GSSG)比率及抗氧化酶...
TargetMol N-Acetylcysteine amide 是一种硫醇抗氧化剂,也是一种神经保护剂,能够透过细胞膜和血脑屏障的,可降低ROS 的产生。 所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。 分子量 162.21 分子式 C5H10N2O2S CAS No. 38520-57-9 ...
溶解性数据 forN-Acetylcysteine amide 溶剂最高浓度 mg/mL最高浓度 mM 溶解性 water16.22100 DMSO16.22100 制备储备液 forN-Acetylcysteine amide 以下数据基于产品分子量162.21。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volum...
N-Acetylcysteine amide,又称N-乙酰半胱氨酸酰胺,一种新型硫醇化合物,是抗氧化剂和神经保护剂,通过调节 NF-κB 和 HIF-1α的激活,降低ROS水平,表现出抗炎活性。N-Acetylcysteine amide能够透过细胞膜和血脑屏障,在神经退化和氧化介导的疾病治疗中具有潜在研究价值。
产品活性:N-Acetylcysteine amide 是一种能透过细胞膜和血脑屏障的硫醇抗氧化剂和神经保护剂,可降低 ROS 的产生。 体外:N-乙酰半胱氨酸酰胺对用阿霉素 (DOX) 处理的 H9c2 细胞在过氧化氢酶 (CAT)、谷胱甘肽过氧化物酶 (GPx)、谷胱甘肽还原酶 (GR) 等酶上的活力没有明显影响[1]。N-乙酰半胱氨酸酰胺 (1 ...
N-acetylcysteine amide CAS:38520-57-9 产品活性:Although NACA effectively reduced oxidative stress in DOX-treated H9c2 cells, it had minimal effects on DOX-induced cell death. NACA prevented oxidative stress by elevation of GSH and CYS, reduction of ROS and lipid peroxidation, and restoration of ...
N-Acetylcysteine amide structure CAS No. 38520-57-9 Chemical Name: N-Acetylcysteine amide Synonyms AD4;NACA;100951;acetylcysteinamide;N-ACETYL-L-CYSTINE;N-acetylcysteine amide;N-Acetyl-L-cysteinamide;N-acetyl-L-Cysteine amide;Acetylcysteine Impurity 14;(R)-2-acetaMido-3-MercaptopropanaMide ...
化学名称:N-Acetylcysteine Amide 化学别名:(2R)-2-(Acetylamino)-3-mercaptopropanamide; CAS号:38520-57-9 分子式:C₅H₁₀N₂O₂S 性状:White to Off-White Solid Melting Point:146- 149°C 分子量:162.21 存储条件:-20°C 溶解度:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly...
Shakila TobwalaEylem Y. PinarciYasaswi MaddiralaNuran Ercal生物化学进展(英文)Tobwala S, Pinarci EY, Maddirala Y, Ercal N. N-acetylcysteine amide protects against dexamethasone-induced cataract related changes in cultured rat lens- es. Advances in Biological Chemistry. 2014;4(1):9....
N-acetylcysteine amide, a promising antidote for acetaminophen toxicityGSH-prodrugAcetaminophenHepatotoxicityOxidative stressNAPQIGlutathioneAcetaminophen (N-acetyl-p-aminophenol, APAP) is one of the most widely used over the counter antipyretic and analgesic medications. It is safe at therapeutic doses, ...