N-Acetylcysteine (NAC) is widely used in respiratory medicine, with a maximum licensed dose in chronic use of 600 mg/day; however, some clinical trials have studied the efficacy of NAC at higher doses. The aim of this review was to evaluate the adverse effects profile of NAC at higher ...
Findings of case studies and small placebo-controlled studies suggest that NAC 600mg to 2400mg/day may ameliorate symptoms of compulsive hair pulling (trichotillomania), nail-biting and skin-picking. Subjects diagnosed with pathological gambling who responded to NAC 1800mg/day in an 8-week open-...
This study was performed to confirm the efficacy of a 6-month therapy with a formulation of N-acetylcysteine (NAC; 600 mg/day p.o.) on frequency and severity of exacerbations in patients suffering from chronic obstructive pulmonary disease (COPD). One hundred sixty-nine patients attending five...
Our product comes in the form of vegetarian capsules, each of which contains 600mg of N-acetylcysteine. Though the dose can vary depending on individual need, 1 to 3 capsules a day is generally the amount recommended. Taking vitamin C at the same time can also be beneficial in helping to...
N-Acetylcysteine was given intravenously and as three fast dissolving and one slow-release formulation, on separate occasions, as a single dose of 600 mg to 10 fasting (5 men and 5 women) healthy volunteers. Blood and urine were sampled for the following 12 h.Renal clearance constituted around...
Toxicity data of this and other studies confirm that a long-term daily usage of NAC in a 600mg dose is safe and may be recommended for clinical chemopreventive research.doi:10.1016/0169-5002(96)85843-0NoneDepartment of Chest Oncology, HET Nederlands Kanker Institute, 1066 CX Amsterdam, The ...
Patients were divided into 2 groups: the NAC group (31 patients receiving 600-mg NAC daily for 3 months) and the control group (29 patients with no prophylactic medication). CRPS-1 diagnosis was based on Budapest criteria during multiple follow-up visits. Serum levels of interleukin (IL)-1...
N-acetylcysteine (600 mg/day) was given to patients by mouth for five days before bronchoscopy and bronchoalveolar lavage to determine whether N-acetylcyst... MM Bridgeman,M Marsden,MacNee, W.,... - 《Thorax》 被引量: 290发表: 1991年 加载更多来源...
In this 3-month randomized controlled trial, 74 participants with RA were randomized to take 600 mg of NAC (36 participants; 30 women, 6 men) or a placebo (34 participants; 24 women, 10 men) twice per day. Disease activity was assessed before and after the study using the Disease Activi...
600-1500 mg/day in 3 divided doses Chronic Bronchitis (human) Smilkstein MJ et al. N Engl J Med 319: 1557- 1562, 1988. 140 mg/kg followed by 17 subsequent doses of 70 mg/kg every 4 h Acetaminophen Poisoning (human) Reference Dosage Disease ...