The acidic dipeptide, N-acetylaspartylglutamate (NAAG), was discovered in the mammalian nervous system in 1965, but initially was not considered to be a neurotransmitter candidate. In the mid-1980s, a few laboratories revisited the question of NAAG's role in the nervous system and pursued ...
N-Acetylaspartylglutamate (NAAG) is a nervous system-specific, acidic dipeptide which is released from neurons in a manner consistent with a function in synaptic neurotransmission. The hydrolysis of NAAG to produce glutamate and N-acetylaspartate was analyzed in cell cultures prepared from murine ...
N-Acetylaspartylglutamate (NAAG) is the third most prevalent neurotransmitter in the mammalian nervous system, yet its therapeutic potential is only now being fully recognized. Drugs that inhibit the inactivation of NAAG by glutamate carboxypeptidase II (GCPII) increase its extracellular concentration and...
NAAGneuronpostmortemrat CNSN-acetyl aspartate (NAA), a putative marker of neuronal injury, can be measured non-invasively in patients by magnetic resonance spectroscopy (MRS). Interpretation of in vivo MRS data, however, requires neuropathological correlates to NAA alterations using autopsy or ...
N-Acetyl-aspartyl-glutamate [glutamate-3,4-3H] NAAG [glutamate-3,4-3H] 中文名: 中文别名: CBNumber: CB312201502 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商1 N-Acetyl-aspartyl-glutamate [glutamate-3,4-3H] NAAG [glutamate-3,4-3H]化学性质 ...
SimultaneousdeterminationmethodofN-acetyl-l-aspartyl-l-glutamate(NAAG),anendogenousago- nistattype3metabotropicglutamatereceptor,anditsdegradationproduct,N-acetyl-l-aspartate (NAA)wasdevelopedbyusingreversed-phasehigh-performanceliquidchromatography(HPLC)with pre-columnfluorescencederivatizationusing4-N,N-dimethyla...
N -acetylaspartylglutamate (NAAG), a dipeptide derivative of N -acetylaspartate (NAA) and glutamate (Glu), is present in neurons. Upon neurostimulation, NA... MH Baslow,VV Dyakin,KL Nowak,... - 《Journal of Molecular Neuroscience》 被引量: 24发表: 2005年 Brain Effects of Growth Hormone...
英文名称:N-Acetyl-aspartyl-glutamate [glutamate-3,4-3H] NAAG [glutamate-3,4-3H] 英文同义词:N-Acetyl-aspartyl-glutamate [glutamate-3,4-3H] NAAG [glutamate-3,4-3H] CAS号: 分子式: 分子量:0 EINECS号: 信息错误报告 您的Email: 按国家浏览N-Acetyl-aspartyl-glutamate [glutamate-3,4-3H] NAAG...
Yamamoto T, Kozikowski A, Zhou J, Neale JH. Intracerebroventricular administration of N-acetylaspar- tylglutamate (NAAG) peptidase inhibitors is analgesic in inflammatory pain. Mol Pain. 2008; 4: 31. doi: 10.1186/1744-8069-4-31 PMID: 18673570...
Recently, N-acetylaspartylglutamate (NAAG) has been proposed as a neurotransmitter in mammalian optic pathway; however, the release of endogenous NAAG on stimulation of the optic pathway has not been demonstrated. Using an in vivo microdialysis technique, we now report that electrical stimulation of...