CHLAMYDOMONASGREEN algaeRED algaeCELLULAR signal transductionPROTEINSARGININEN-Acetyl-L-glutamate kinase (NAGK) catalyzes the rate-limiting step in the ornithine/arginine biosynthesis pathway in eukaryotic and bacterial oxygenic phototrophs. NAGK is the most highly conserved target of t...
Site-directed mutagenesis studies on the L-arginine-binding sites of feedback in N-acetyl- L-glutamate kinase ( NAGK) from Corynebacterium glutamicum [J]. Curr Microbiol,2012,64( 2) : 164-172.Xu M J; Rao Z M; Dou W F;.Site-directed mutagenesis studies on the L-arginine-binding sites...
N-Acetyl-L-glutamate kinase (NAGK) is a key enzyme in the synthesis of L-arginine. Although solving the problem of L-arginine feedback inhibition for NAGK is a vital way for improving L-arginine production, an equally important mechanism is improving catalytic activity and thermostability of ...
N‐acetyl‐l‐glutamate kinaseNonphotosynthetic plastidsPII‐signallingTCA/GS‐GOGAT cyclesDuring evolution, several algae and plants became heterotrophic and lost photosynthesis, however, in most cases, a non﹑hotosynthetic plastid was maintained. Among these organisms, the colorless alga Polytomella ...
Site-directed mutagenesis and feedback-resistant N-acetyl-L-glutamate kinase (NAGK) increase Corynebacterium crenatum L-arginine production. Amino Acids 43, 255-266.Meijuan Xu,Zhiming Rao,Wenfang Dou,Juan Yang,Jian Jin,Zhenghong Xu.Site-directed mutagenesis and feedback-resistant N-acetyl- L -...
L-ArginineCorynebacteriumcrenatumN-acetyl-l-glutamate kinase (NAGK) catalyzes the second step of l-arginine biosynthesis and is inhibited by l-arginine in Corynebacterium crenatum. To ascertain the basis for the arginine sensitivity of CcNAGK, residue E19 which located at the entrance of the ...
Site-directed mutagenesis and feedback-resistant N-acetyl-L-glutamate kinase (NAGK) increase Corynebacterium crenatum L-arginine production[J].Amino acids 2012,1(1).Meijuan Xu Zhiming Rao Wenfang Dou . Site-directed mutagenesis and feedback-resistant N-acetyl-L-glutamate kinase (NAGK) increase ...
We created a model of acetylglutamate kinase enzyme 3D-structure as template with Molsoft ICM v3.5 software. The Internal Coordinate Mechanics (ICM) homology modeling algorithm has demonstrated excellent accuracy in blind predictions. Moreover, recent results showed that models built with as little as...
We created a model of acetylglutamate kinase enzyme 3D-structure as template with Molsoft ICM v3.5 software. The Internal Coordinate Mechanics (ICM) homology modeling algorithm has demonstrated excellent accuracy in blind predictions. Moreover, recent results showed that models built with as little as...
Increased L-arginine Production by Site-directed Mutagenesis of N-acetyl-L-glutamate Kinase and pro B Gene Deletion in Corynebacterium crenatum[J]. ZHANG Bin,WAN Fang,QIU Yu Lou,CHEN Xue Lan,TANG Li,CHEN Jin Cong,XIONG Yong Hua.Biomedical and Environmental Sciences. 2015(12)...