n-3多不饱和脂肪酸(n-3PUFAs),因多不饱和脂肪酸中第一个不饱和键出现在碳链甲基端的第三位,称之为n-3脂肪酸,也叫ω-3多不饱和脂肪酸。...查看全部内容 关注话题管理 分享 百科 讨论 精华 等待回答Omega-3食物排行榜(包括肉类、蔬菜、水果、坚果...) 康氏健康说 基于康景轩教授脂类医学及...
【Omega-3脂肪酸(n-3 PUFAs)#是大脑功能成熟的必要条件】母体饮食中n-3 PUFA的缺乏会增加啮齿动物发育中的海马突触元素的小胶质细胞介导的吞噬作用,改变神经元形态,影响后代的认知能力。脂类是中枢神经系统(CNS)的主要成分之一。其中,花生四烯酸(AA,20:4n-6)和二十二碳六烯酸(DHA,22:6n-3)是灰质长链(LC)多...
注意到,两种干预后的空腹血糖均显著升高,其中较高剂量维生素E组升高幅度更大(11% VS 9%),这可能归因于更大的肝损伤导致的肝胰岛素抵抗。 n-3提高外周胰岛素敏感度 与其他PUFA一样,n-3(特别是在有维生素E的情况下)短期内可提高外周胰岛素敏感度,从而下调一部分空腹胰岛素。 文献[17]的交叉试验显示,与单独补充n...
Long chain omega-3 polyunsaturated fatty acids (n-3 PUFA)1 are a distinct class of fatty acids that have multiple double bonds, with the last double bond being located 3 carbons from the terminal methyl (n or ω) end of the chain [1]. They began to attract attention in the 1970's ...
2.1. n-3 PUFAs in Depression and CVD There are two main types of bioactive polyunsaturated fatty acids (PUFAs), the omega-6 (n-6) series (cis-linoleic acid [LA,18 : 2], γ-linolenic acid [GLA, 18 : 3, n-6], dihomo-GLA [20 : 3, n-6], arachidonic acid [AA, 20 : 4, ...
关键词:营养支持;n-3脂肪酸;1,6二磷酸果糖;谷氨酰胺;小肠移植,大鼠 肠外与肠内营养990210 摘要 目的:探讨TPN加用n-3脂肪酸、1,6二磷酸果糖及谷氨酰胺对小肠移植大鼠特殊营养支持的作用及可能机理。 方法:196只近交系Wistar大鼠分别作为供、受体行全小肠异位移植,术前和术后应用n-3脂肪酸灌胃和TPN中加入1,...
N-3 PUFAs have been demonstrated in vitro it could prevent the intestinal tight junctions (TJs) from the ischemia/re-perfusion injury and the inflammatory reaction injury. The purpose of this study was to evaluate the protection of n-3 PUFAs on the intestinal TJs in the rat model of hemorr...
2. OMEGA-3 polyunsaturated fatty acids 2.1. General view N-3 PUFAs are found mainly in plants and marine sources, primarily from cold-water fish (Friedman & Moe, 2006). In animals, α-linolenic acid (18:3n-3) can be converted to stearidonic acid (18:4n-3) by delta-6 desaturase, ...
Intrauterine growth restriction (IUGR) predisposes to chronic kidney disease via activation of proinflammatory pathways, and omega-3 PUFAs (n-3 PUFAs) have anti-inflammatory properties. In female rats, we investigated 1) how an elevated dietary n-3/n-6 PUFA ratio (1:1) during postnatal kidney...
Similar relationships were seen for death from cardiovascular disease, cancer and other causes. No associations were seen with the 18-carbon omega-3, alpha-linolenic acid. These findings suggest that higher circulating levels of marine n-3 PUFA are associated with a lower risk of premature death....