Qikai Sun, Quanquan Wang, Wenzhuo Qin, Kaiyu Jiang, Gang He, Ming Joo Koh & Gong Chen. N-glycoside synthesis through combined copper- and photoredox-catalysed N-glycosylation of N-nucleophiles. Nat. Synth (2024). https://doi.org/10.1038/s44160-024-00496-7 长按扫码,查看原文 ✦ 推荐阅...
Qikai Sun, Quanquan Wang, Wenzhuo Qin, Kaiyu Jiang, Gang He, Ming Joo Koh & Gong Chen. N-glycoside synthesis through combined copper- and photoredox-catalysed N-glycosylation of N-nucleophiles.Nat. Synth2024
Although such ionic glycosylation strategies can effectively form O-glycosides, their use in N-glycoside synthesis is often plagued by the subdued reactivity of N-nucleophiles under the acidic reaction conditions required for glycosyl donor activation. Exploration of the reactivity of glycosyl radical ...
Although such ionic glycosylation strategies can effectively form O-glycosides, their use in N-glycoside synthesis is often plagued by the subdued reactivity of N-nucleophiles under the acidic reaction conditions required for glycosyl donor activation. Exploration of the reactivity of glycosyl radical ...
Sun, Q., Wang, Q., Qin, W.et al. N-glycoside synthesis through combined copper- and photoredox-catalysed N-glycosylation of N-nucleophiles. Nat. Synth (2024) DOI: 10.1038/s44160-024-00496-7 https://www.nature.com/articles/s44160-...
Qikai Sun, Quanquan Wang, Wenzhuo Qin, Kaiyu Jiang, Gang He, Ming Joo Koh & Gong Chen. N-glycoside synthesis through combined copper- and photoredox-catalysed N-glycosylation of N-nucleophiles.Nat. Synth(2024). https://doi.org/10.1038/s44160-024-00496-7...
-lactosyl, -maltosyl, and -melibiosyl azides with various acetylenedicarboxylic acid esters gave the corresponding 1-N-glycobiosyl-1,2,3-triazoles (1a,b,c-8a,b,c) which have been used as glycosyl donors for the synthesis of oligosaccharides (15-17) and an anthracycline type antibiotic (...
A new approach to c-glycoside congeners: Metal carbene mediated methylenation of aldonolactones. - ScienceDirect Versatile intermediates for the synthesis of C-glycosides and oxygen heterocycles are readily available through titanium mediated methylenation of aldonola... CS Wilcox,GW Long,H Suh - 《...
An efficient C-glycoside production platform enabled by rationally tuning the chemoselectivity of glycosyltransferases Article Open access 15 October 2024 References Cereghino, G.P., Cereghino, J.L., Ilgen, C. & Cregg, J.M. Production of recombinant proteins in fermenter cultures of the yeast...
近日,南开大学陈弓教授课题组与新加坡国立大学许民瑜 (Ming Joo Koh)教授课题组合作,开发了光、铜催化糖基砜给体的自由基脱砜C-N偶联合成N-糖苷,高效地实现了一系列有价值的N-糖苷的合成。此外,该反应对水兼容并且对不同的亲核试剂体现出了较好的化学...