N-acetylcysteine (NAC) is a potent antioxidant derived from the amino acid L-cysteine and is used for the treatment of various conditions such as schizophrenia, amyotrophic lateral sclerosis, bipolar disorder, Alzheimer’s disease and various cancers27. We hypothesise that NAC may alleviate olanzapine...
N-acetylcysteineToxicityObesityOverdoseA capped NAC dosing scheme was not associated with higher rates of hepatic injury or hepatotoxicity in obese patients in the setting of acetaminophen poisoning when compared to a non-capped regimen. Further research is needed to verify these results....
OPEN Citation: Transl Psychiatry (2015) 5, e492; doi:10.1038/tp.2014.131 www.nature.com/tp ORIGINAL ARTICLE N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's disease DJ Wright1,2, T Renoir1, ZM Smith3, AE Frazier4,5,...
Chen G, Shi J, Hu Z, Hang C. Inhibitory effect on cerebral inflammatory response following traumatic brain injury in rats: a potential neuroprotective mechanism of N-acetylcysteine. Mediat Inflamm. 2008;2008:716458. doi:10.1155/2008/716458. Ellis EF, Dodson LY, Police RJ. Restoration of cere...
n-AcetylcysteineCocainePharmacotherapySelf-administrationAttentional biasHumanBackground: Disrupted glutamate homeostasis is thought to contribute to cocaine-use disorder, in particular, by enhancing the incentive salience of cocaine stimuli. n-Acetylcysteine might be useful in cocaine-use disorder by ...
591: AN ESTABLISHED DOSING OF N-ACETYLCYSTEINE IN NON-ACETAMINOPHEN-INDUCED ACUTE LIVER FAILUREdoi:10.1097/01.ccm.0000509269.14045.f2Justin KinneyNam ChoCritical Care MedicineSharma M, Verma N. N-acetylcysteine in non-acetaminophen pedia- tric acute liver failure: recent evidence. Indian Pediatr 20...
Weight-based N-acetylcysteine dosing chart to minimise the risk of calculation errors in prescribing and preparing N-acetylcysteine infusions for adults presenting with paraceta- mol overdose in the emergency department. Emerg. Med. J. 2007; 24: 482-4....
962: INCREASED INTRAVENOUS N-ACETYLCYSTEINE DOSING FOLLOWING MASSIVE ACETAMINOPHEN INGESTIONdoi:10.1097/01.ccm.0000551710.54934.0aAudley, KristenRosini, JamieCritical Care Medicine
Introduction of an N- acetylcysteine weight-based dosing chart reduces prescription errors in the treatment of paracetamol poisoning: Reply. Emerg Med Aust 2013; 25: 285-286.McIntyre S, McD Taylor D, Greene S. Introduction of an N-acetylcysteine weight-based dosing chart reduces prescription ...
Abbreviated dosing of N- acetylcysteine prevents contrast-induced nephropathy after elective and urgent coronary angiography and intervention. J Interv Cardiol 2004;17(3):159-165.Ochoa A, Pellizzon G, Addala S, Grines C, Isayenko Y, Boura J, et al. Abbreviated dosing of N-acetylcysteine ...