Myosin attaches to actin, forming a crossbridge that produces force and movement as it tiltsor rocks into subsequent bound statesbefore finally detaching. It has been hypothesized that the kinetics of one or more of these mechanical transitions are dependent on load, allowing muscle to shorten ...
Acidosis affects muscle contraction by slowing the rates myosin attaches to and detaches from actinFatigueOptical trapModelingPhosphateThe loss of muscle force and power during fatigue from intense contractile activity is associated with, and likely caused by, elevated levels of phosphate (\\(\\mathrm...
However the subsequent course of events remains unclear; there is not even sure evidence that myosin attaches to actin during muscular contraction, although various changes in the X-ray diffraction pattern indicate that it does (Huxley, 1967; Armitage et al., this volume) and it certainly does ...
Put the following in order. a. Myosin kinase attaches phosphate from ATP to myosin heads. b. Calmodulin bound with Ca^2+ binds to myosin kinase. c. Calcium ions bind with calmodulin. d. An alpha subunit opens the Ca^2+ channel in the plasma membrane ... ...
Since this step is only accelerated for the myosin X dimer (HMM) and not for the monomer (S1) on a bundle, the basis of the acceleration must be off-axis strain that is generated when the lead head attaches to a different actin filament from the one to which the rear head is bound....
Model for processive myosin movement along the 36-nm half-helical repeat of actin. (a) Head 1 attaches and produces a working stroke of 20 nm, probably coupled to the release of phosphate (straight arrow). While ADP is still bound to head 1, the unbound head 2 explores the energy ...
___ - bridges form when myosin head binds to active sites on G actin molecules. Fill in the blank. A myosin cross-bridge attaches to actin in order to ___. Which structure surrounds the connection between the spinal cord and the brain? What skeletal...
If both heads of 0-hep zip can attach simultaneously, then neither head can generate a complete powerstroke due to hindrance caused by the neighboring head. Alternatively, only one head attaches and generates the observed displacements. For this case, either the second head blocks the motion-...
To characterize the mechanism through which myosin XI-K attaches to its principal endomembrane cargo, a yeast two-hybrid library of Arabidopsis thaliana cD... VV Peremyslov,EA Morgun,EG Kurth,... - 《Plant Cell》 被引量: 0发表: 2013年 Motoring around the Golgi The is a dynamic organelle...
To demonstrate the method, we subject human β-cardiac myosin subfragment-1 (S1, the motor domain of myosin) to this simplified assay. It yields directly the load dependence of the lifetime of the actin–myosin-bound state at saturating ATP concentration. The inverse of this lifetime is the...