Donor class I MHC antibody induces high levels of myeloperoxidase, perforin and CCL5 during antibody-mediated rejection of heart allograftsY., HattoriK., SetoguchiR.L., Fairchild
Monoclonal Anti-MPO Myeloperoxidase antibody produced in mouse Product information MPO is the most toxic enzyme found in the azurophilic granules of neutrophils.Higher serum levels of MPO have been associated with cardiovascular diseases. Purity: >95% Storage: cool or freezer ...
To investigate presence of circulating myeloperoxidase-positive microparticles (MPO + MPs) in relation to disease activity in patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Forty-six patients with AAV and 23 age- and sex-matched healthy controls were included. ...
No high-dose steroid with intensive immunosuppression or plasma exchange was required. This is a preview of subscription content, log in via an institution to check access. Similar content being viewed by others A case of smoldering antineutrophil cytoplasmic antibody-associated vasculitis development ...
Blots were stripped using buffer containing 62.5 mM Tris–HCl, pH 6.7, 100 mM 2-mercaptoethanol, 2% SDS, at 55 °C for 30 min, and reprobed with the rabbit polyclonal antibodies to PTEN and visualized with HRP-conjugated secondary antibody followed by ECL Plus®. 2.10. Western immuno...
After washing immunoprecipitated proteins in lysis buffer three times, concentrated samples were loaded onto a 4−20% SDS-PAGE gel, transferred onto a PVDF membrane (Millipore) and blotted with anti-Band-3 antibody (Abcam). Plasma MPO activity MPO activity was assayed using a colorimetric assay...
Furthermore, the unusual (truncated) glycosylation pattern on MPO along with the heterogeneity of MPO glycosylation may affect antibody recognition, and in disease states where autoantibodies are generated. Also, antibody recognition may be altered by glycosylation, where a minor decrease in recognition ...
Hydrogen peroxide (H2O2) is a relatively long-lived signaling molecule that plays an essential role in oocyte maturation, implantation, as well as early embryonic development. Exposure to relatively high levels of H2O2 functions efficiently to accelerate oocyte aging and deteriorate oocyte quality. Howev...
Intravascular large B-cell lymphoma with a high titer of proteinase-3-anti-neutrophil cytoplasmic antibody mimicking granulomatosis with polyangiitis Mod. Rheumatol., 29 (1) (2019), pp. 195-197 CrossrefView in ScopusGoogle Scholar [95] J.D. Edgar, D.P. Rooney, P. McNamee, T.A. McNeill ...
Autoreactivity to myeloperoxidase (MPO) causes anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), with rapidly progressive glomerulonephritis. Here, we show that a Staphylococcus aureus peptide, homologous to an immunodominant MPO T