ACUTE kidney failureBackground and Objectives: The clinical presentation and survival factors in patients with myeloma-related kidney impairment (MRKI) at diagnosis remain a topic of ongoing research, given the complex interplay between nephrology and hematology. To date, no st...
This condition often presents with bone pain, primarily in the spine and ribs, though other locations are also commonly affected. The pain typically worsens with movement. Other common symptoms include chronic or acute infection, anemia, and kidney failure. However, myeloma is so varied in its fo...
Renal failure (RF) occurs in approximately 20-30% of multiple myeloma (MM) patients at diagnosis and in more than 50% of patients with advanced disease. The pathogenesis of RF is related to the production of monoclonal light chains that can damage either the tubule (myeloma kidney) or the ...
2024 High performing in leukemia, lymphoma and myeloma; colon and prostate cancer surgeries, heart attacks and heart failure; kidney failure; and pneumonia. Nicole Villalpando, Austin American-Statesman, 17 July 2024 Once myeloma returns, previous treatments become less effective at keeping the cancer...
Kidney problems.Yourkidneyshave to work overtime to filter out the M proteins and calcium in your blood. Your kidneys might not work as well as they should, or you might even have kidney failure. Types of M Proteins M proteins are made of pieces called chains. There are usually two "lig...
The most common cause of death related to multiple myeloma isinfection, with pneumonia being the most common fatal infection. Other common causes of death are bleeding (from low platelet counts), complications of bone fractures, kidney failure, and blood clots in the lungs. ...
Current Approach to Diagnosis and Management of Acute Renal Failure in Myeloma Patients Renal impairment is a serious complication of multiple myeloma. The primary cause of renal failure in myeloma is damage to the kidney by excessive amounts ... N Leung,J Behrens - 《Advances in Chronic Kidney...
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Plasmapheresisis an uncommon treatment that can be used to manage something called myeloma kidney, a type of kidney failure that affects many people withmultiple myeloma. It separates outplasmafrom the rest of your blood. It's a way to remove abnormal proteins and other harmful substances from ...
Myeloma and the Kidney Ashley B. Irish, in Comprehensive Clinical Nephrology (Fourth Edition), 2010 Etiology and Pathogenesis of Myeloma Myeloma is an incurable B cell–derived malignant neoplasm of incompletely differentiated plasma cells that have two prominent features, increased production of monoclona...