Mycophenolate mofetil is a white to off-white crystalline powder. It is slightly soluble in water (43 μg/mL at pH 7.4); the solubility increases in acidic medium (4.27 mg/mL at pH 3.6). It is freely soluble in acetone, soluble in methanol, and sparingly soluble in ethanol. The apparen...
Mycophenolate mofetil is a commonly used immunosuppressive medication in the postliver transplant setting where gastrointestinal side effects tend to predominate. However, in more recent times, emerging and rare side effects are being reported in the literature. We present a case of a patient who had...
EXPERT OPINION Mycophenolate mofetil for myasthenia gravis: a clear and present controversy Chad Heatwole Emma Ciafaloni Department of Neurology, The University of Rochester, Rochester, New York, USA Correspondence: Chad Heatwole Department of Neurology,The University of Rochester, Rochester, NewYork, ...
Mycophenolate mofetil is a prodrug that inhibits guanine synthesis, leading to reduced proliferation of T and B cell lymphocytes. It has shown potential as an add-on therapy to β-interferon for multiple sclerosis treatment, with a significant reduction in relapse rates. However, it is also associ...
Potential side effects are significant, and failure to achieve remission is still high. Mycophenolate mofetil (MMF) has emerged as a potential alternative to CYC, with an improved safety profile thus far. Results of two mayor randomized controlled trials in adults indicate no evidence of inferiority...
Rediscovering mycophenolic acid: a review of its mechanism, side effects, and potential uses. J Am Acad Dermatol. 1997;37445- 449Google ScholarCrossref 14. Neyts JAndrei GDe Clerq E The novel immunosuppressive agent mycophenolate mofetil markedly potentiates the antiherpesvirus activities of acyclovir...
Our Myhibbin (mycophenolate mofetil oral suspension) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. Call your doctor for medical advice...
Based on animal data, men should not donate semen during therapy and for 90 days following discontinuation of mycophenolate mofetil [see Use In Specific Populations (8.3)]. 5.13 Effect of Concomitant Medications on Mycophenolic Acid Concentrations A variety of drugs have potential to alter systemic...
Mycophenolate mofetil, with the chemical formula C23H31NO7, has the CAS number 115007-34-6. It is a prodrug of mycophenolic acid, which is an immunosuppressive drug. Mycophenolate mofetil appears as a white to off-white crystalline powder. It does not have a distinct odor. The basic structure...
Mycophenolate Mofetil (MMF) has been registered for use in Australia since 1997 for prophylaxis of solid organ allograft rejection. MMF is now increasingly used for indications outside solid organ allograft rejection, often with limited supporting efficacy data. The purpose of this audit was to exami...