basic reproduction ratecritical community sizemaintenance hostmycobacteriaR0reservoir hostspillover hosttuberculosiswildlifeMycobacterium bovis is the cause of tuberculosis in animals and sometimes humans. Many developed nations have long-standing programmes to eradicate tuberculosis in livestock, principally cattle...
Among 60 animals tested, 20 samples (33.3%) showed negative results for both MTBC and NTM infection. Eighteen samples (30%) showed positive responses against PPD from M. bovis and/or ESAT6 and CFP10, indicating MTBC infection. In contrast, only 15.6% showed seropositivity in a commercial ...
…most important species of which,M. tuberculosisandM. leprae,cause tuberculosis and leprosy, respectively, in humans.M. boviscauses tuberculosis in cattle and in humans. Some mycobacteria are saprophytes (i.e., they live on decaying organic matter), and others are obligate parasites. Most are...
The lipid composition performs important functions in interaction between macropha-ge and Mycobacterium tuberculosis (MTB)/Mycobacterium bovis (MB). Current understanding regarding the lipid responses of bovine alveolar macrophage (BAM) to MTB/MB is quit
bovis, M. africanum, M. microti) and the M. avium complex [1]. M. bovis, which is the causative agent of tuberculosis in domestic cattle, wild and domestic animals, and occasionally in humans, is of concern throughout the world [2, 3]. M. tuberculosis complex infections are ...
More specifically, 64.5% of genes in the affects immune response subcategory displayed decreased relative expression levels in the infected animals compared to the control group. Conclusions This study demonstrates that genome-wide transcriptional profiling of PBL can distinguish active M. bovis-infected ...
However, this first required that we established that these mice could reproduce the main histopathological features of bTB development in cattle. In the present study we showed that, following M. bovis intranasal infection, the C3HeB/FeJ mouse model recapitulated the classical granuloma found in ...
bovis culture filtrate proteins (CFP) and a copolymer as the adjuvant was performed in tuberculin skin test-negative cattle (TST-), while TST reactor animals (TST+) received EEP-1 only. Booster immunization using EEP-1 was applied to both groups, 2 months after primary vaccination to whole ...
Of the examined animals, one boar and two sows from Madudu Sub County were infected with M. bovis which presented as lesions of a deep yellow colour and a grit-like texture in the mesenteric lymph nodes. This represents 2% (3/150) of the lymph nodes where lesions suggestive of mycobacteri...
M. bovisisolates that are cultured from skin test-reactor animals are currently genetically typed using a combination of spoligotyping [2] and VNTR [3]. Spoligotyping exploits a polymorphic region of the genome called the DR locus which consists of multiple, identical 36bp repeats interspersed with...