Immunogen Recombinant fusion protein of human MYBBP1A (NP_055335.2). Abbre MYBBP1A Synonyms MYBBP1A, P160, PAP2, Pol5 Swissprot Q9BQG0 Cellular Localization Cytoplasm. Nucleus. Nucleus>nucleolus. Shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export app...
MYBBP1A primary antibody included. Planning an IF experiment? We recommend our CoraLite® Plus 488 and CoraLite®594 conjugated versions of this antibody. 推荐稀释比 ApplicationDilution Western Blot (WB) WB : 1:5000-1:50000 Immunohistochemistry (IHC) IHC : 1:500-1:2000 Immunofluorescence (IF...
L28829MYBBP1A基因敲除HEK293T细胞Trizol裂解液500µl1258.00元 pLenti-MYBBP1A-sgRNA (MYBBP1A基因敲除质粒)是一种在动物细胞中可以同时表达Cas9、目的基因的sgRNA和puromycin抗性基因的质粒。用于在动物细胞中直接基于CRISPR/Cas9技术敲除目的基因,或者通过包装慢病毒后基于CRISPR/Cas9技术敲除目的基因。本质粒中sgRNA的有...
Recently, we found that a nucleolar protein, Myb-binding protein 1a (MYBBP1A), was involved in p53 activation. However, the function of MYBBP1A in cancer prevention has not been elucidated. Methods Relationships between MYBBP1A expression levels and breast cancer progression were examined using ...
MYBBP1A 基因简介 中英文全称:MYB 结合蛋白(P160)1a MYB binding protein (P160) 1a 分布:核|核仁|细胞质|NLS 依赖蛋白核输入复合 体 活性:DNA结合|DNA引导DNA聚合酶 参与:转录|调 控转录, DNA依赖|核/质运输 OMIM/位置:604885 17p13.3
MYBBP1A is a powerful negative regulator of PPAR gamma coactivator 1 alpha (PGC-1 alpha) by p38 MAPK and also acts as a nucleocytoplasmic shuttling protein that utilizes CRM1-dependent and independent nuclear export pathways. 仅用于科研。不用于诊断过程。未经明确授权不得转售。
揭示了p53 和 NAT10 相互依存地合作形成一个促进心肌细胞铁死亡以加剧心脏 I/R 损伤的正反馈回路,这表明靶向 NAT10/Mybbp1a/p53 轴可能是治疗心脏 I/R 的新方法。 研究人员新发现: (1) 在缺血/再灌注损伤的心肌细胞中,Nat10mRNA和蛋白水平显著升高;(2)P53作为转录激活剂上调了缺血/再灌注损伤的心肌细胞Nat...
此外,Mybbp1a的下调部分消除了NAT10过表达对心肌细胞铁凋亡和心脏I/R损伤的有害影响。总的来说,该研究揭示了p53和NAT10相互依赖地合作形成一个正反馈回路,促进心肌细胞铁下沉,加剧心脏I/R损伤,这表明靶向NAT10/Mybbp1a/p53轴可能是治疗心脏I/R的新方法。
MYBBP1A Knockout Lentivirus(MYBBP1A基因敲除慢病毒)是一种感染动物细胞后可以同时表达Cas9、目的基因sgRNA和puromycin抗性基因的慢病毒。本产品用于在动物细胞中基于CRISPR/Cas9技术敲除目的基因,并且本慢病毒中sgRNA的有效性已经通过T7EI法的验证。 本慢病毒基因序列的关键图谱信息请参考图1。本慢病毒可用于感染细胞或...
产品名称:Mouse anti-MYBBP1A Monoclonal Antibody 产品别名:MYBBP1A抗体 宿主:Mouse 反应种属:Human 克隆性:Monoclonal Antibody 保存方法:Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. ...