a满足了温饱才能做其它事 Satisfied the warm and sufficient condition to be able to make other matters[translate] aWhat do you want? 你想要什么?[translate] aas a result of activating mutations of the upstream regulators, 由于在上游管理者的激活的变化,[translate]...
Are the mutations that cause Huntington's disease the result of a mistake in DNA replication or transcription? Explain.Genes and Protein Production:Generally, when a protein is consistently produced improperly, the root of the issue is first suspected...
A number of unexplained features of ageing can be accounted for if cellular ageing is due to dominant or co-dominant mutations. The experimental evidence both for and against this hypothesis is weak, but experiments involving direct testing are possible. DOI: 10.1016/0022-5193(82)90131-X 被引...
The limited number of recombination events in such vegetatively propagated crops may result in an accumulation of deleterious alleles throughout the genome6. Thus, mutation burden in cassava is expected to be more severe than that in sexually propagated species. Deleterious mutations are considered to...
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Gap junctions are assemblies of intercellular channels that regulate a variety of physiologic and developmental processes through the exchange of small ions and signaling molecules. These channels consist of connexin family proteins that allow for diversity of channel composition and conductance properties. ...
Mutations in the PTPN11 gene are associated with various developmental disorders, hematologic malignancies, and solid tumors, playing distinct biological roles in different mechanisms of cancer development [12,13]. Through the PI3K/AKT/GSK3β signaling pathway, PTPN11 has been shown to promote the pro...
This paper led to assertions that certain forms of cancer are mainly the result of "bad luck", and suggested that these types would be relatively resistant to prevention efforts. The question of random mutations and "bad luck" on cancer brought the question of prominence of environmental (...
The result is that the two genes are spliced together. This fusion gene can then be amplified by a second PCR. A major advantage of this method over conventional recom-binant mutagenesis techniques isthat there is no requirement for unique restriction sites at the point of gene fu-sion/...
Looking across all 32 cancer types studied, the researchers estimated that 66 percent of cancer mutations result from copying errors, 29 percent can be attributed to lifestyle or environmental factors, and the remaining five percent are inherited. "We hope that this research offers comfort to the...