Muscular System is a set of an organ system which are mainly responsible for movement of the human body. It primarily consists of skeletal, smooth and cardiac muscles.
Schematic diagram of the T-cell receptor excision circle (TREC)/kappa-deleting recombination excision circle (KREC)/survival motor neuron 1 (SMN1) newborn screening, diagnostic, and treatment integration system. PCR polymerase chain reaction, SCID severe combined immunodeficiency, XLA X-linked agammagl...
SMA is a chronic, costly disease and nonadherence may further increase the economic impact to both patients and the US health care system. Because of the need for ongoing medical management and frequent hospitalizations, patients with SMA unsurprisingly incur substantially greater health care costs than...
Figure 5 Diagram of the insertion/deletion mutation involving intron 10 of the LARGE gene. The EST DA935254, normally located at 100 kb centromeric of LARGE, is duplicated together with B40 kb of flanking DNA and likely inserted into intron 10 of LARGE. Numerous repetitive elements, which may...
China University of Geosciences (Beijing), Beijing 100083, China 2 Division of Intelligent and Biomechanical System, State Key Laboratory of Tribology, Tsinghua University, Beijing, 100084, China 3 Jockey Club Rehabilitation Engineering Centre, The Hong Kong Polytechnic University, Hong Kong, China yang...
9.1. Eccentric contraction and heat dispersion The production of metabolic heat and its disposal, may be modeled through a central "heat producer" nucleus, made up of skeletal muscles, bowels, internal organs and the central nervous system, a "means of transport", made up of the circulatory ...
In the TALEN system, the two TALE domains are the DNA-recognizing/binding part and the two FokI domains are the DNA-cleavage part12, whereas in the CRISPR-Cas9 system, the single guide-RNA (gRNA) is responsible for DNA-recognizing/binding and the Cas9 endonuclease acts to cleave DNAs13. ...
While CRISPR technology has been used successfully in early studies of genome editing, this is the first report in which a CRISPR/dCas9 system has been used to ameliorate pathogenic gene expression in FSHD. This is also, to our knowledge, the first time the technique has been used successfully...
A measurement device suitable to measure a force, pressure, or load applied by the muscular-skeletal system is disclosed. The measurement module includes a unitary circuit board tha
For Quantitative RT-PCR, 2.0 μg RNA samples were reverse-transcribed to cDNA by using random hexamers and MMLV reverse transcriptase (Life technologies) in 20 μl reaction system. In each analysis, 0.1 μl cDNA pool was used for quantitative PCR. The relative expression of interested genes ...