Because creatinine is a derivative of creatine phosphate, an energy source present in the skeletal muscles, serum creatinine levels are influenced by muscle mass. Elderly people with less muscle mass have low creatinine levels, which may lead to an overestimation of their true renal function. ...
Serum creatinine (SCr) has been widely used to estimate glomerular filtration rate (GFR). Creatinine generation could be reduced in the setting of low skeletal muscle mass. Thus, SCr has also been used as a surrogate of muscle mass. Low muscle mass is associated with reduced survival in hospi...
Aims In chronic heart failure (CHF), low body mass as a reflection of low muscle mass has been associated with poor outcome. Urinary creatinine excretion rate (CER) is an established marker of muscle mass, but has not been investigated in CHF. This study aims to evaluate urinary CER as a...
Estimation of creatinine clearance requires knowledge of creatinine generation which can vary in different groups of patients. Since the main source of creatinine is muscle we used dual-energy X-ray absorptiometry to measure the mass of muscle in a cohort of adult men and women in Rochester, Minn...
Many peritoneal dialysis (PD) patients are malnourished, which leads to weakening owing to a decrease in muscle mass. However, this straightforward association could differ based on the sex of individuals. Further, studies on the sex-based association am
In a correlation analysis, sex, BMI, serum creatinine levels, HbA1c levels, and PMI were positively correlated with FN-BMD, whereas age, history of bone fracture, difficulty in walking and bone-specific alkaline phosphatase level were negatively correlated. In the multivariate regression analysis ...
On the average, water constitutes 75 percent of the wet weight of muscle. Proteins account for most of the solid mass. A distinction is made between the myofibrillar contractile proteins (myosin and actin and their complex—actomyosin—tropomyosin, α andβactins, troponin, and others) and the...
762 patients receiving HD 3 times weekly from July 1, 2001, through June 30, 2006, we examined whether body mass index (BMI) (calculated using 3-month averaged post-HD dry weight) and 3-month averaged serum creatinine levels (a likely surrogate of muscle mass) and their changes over time...
Baseline data comprised demographics, a spectrum of body composition parameters incorporating weight, height, body mass index (BMI), laboratory results incorporating alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin, albumin, creatinine, sodium, prothrombin time-international no...
Third, CKD was assessed using a single-point eGFR value based on creatinine levels. Therefore, the prevalence of CKD could not be confirmed by observing potential transient changes in creatinine. Finally, this was a cross-sectional study, which limited the ability to establish causality. Future ...