Examines differences in skeletal and muscle mass with aging in black and white women. Pattern of involutional change in skeletal and muscle mass; Effects of nutritional and hormonal influences on mass; Factors responsible for the preservation of muscle mass.Aloia...
Skeletal muscle aging is characterized by the loss of both muscle mass and strength, often leading to sarcopenia4. This is a major contributory factor to falls and fractures in older adults, the second-leading cause of injury and deaths5. During aging, there is a selective decrease in both t...
Age-related loss of muscle mass and strength. J Aging Res. 2012;2012:158279. PubMed PubMed Central Google Scholar Terracciano C, Celi M, Lecce D, et al. Differential features of muscle fiber atrophy in osteoporosis and osteoarthritis. Osteoporos Int. 2013;24:1095–100. CAS PubMed ...
range of skeletal muscle biology is included: development, metabolism, the regulation of mass and function, aging, degeneration, dystrophy and regeneration. The emphasis is on understanding adult skeletal muscle, its maintenance, and its interactions with non-muscle cell types and regulatory modulators....
But at some point in your 30s, you start to lose muscle mass and strength. You keep losing muscle as you age. If you lose so much strength and muscle mass that you struggle with basic daily activities, you may be diagnosed with age-related sarcopenia or sarcopenia with aging. Everyone ...
One of the distinctive features of aging is the progressive loss of muscle mass and physical function, collectively known as sarcopenia3. The loss of skeletal muscle mass and tissue function has been related to mobility impairments4, such as difficulties walking short distances or standing up from...
chronic kidney disease, liver disease, chronic heart failure, and chronic obstructive pulmonary disease based on the literature in clinical studies. In addition, the responses in men and women to the commonly used therapeutic agents and their efficacy to improve muscle mass and function are also ...
Loss of lean body mass (LBM) is a common occurrence after treatment for breast cancer and is related to deleterious metabolic health outcomes [Clin Oncol, 22(4):281–288, 2010; Appl Physiol Nutr Metab, 34(5):950–956, 2009]. The aim of this research is to determine the effectiveness ...
Age-associated loss of OPA1 in muscle impacts muscle mass, metabolic homeostasis, systemic inflammation, and epithelial senescence. Cell Metab. 25, 1374–1389.e1376 (2017). CAS PubMed PubMed Central Google Scholar Pereira, R. O. et al. OPA1 deficiency promotes secretion of FGF21 from ...
Measurements of skeletal muscle cross-sectional area (SMA) at the level of the third lumbar (L3) vertebra derived from clinical computed tomography (CT) scans are commonly used in assessments of sarcopenia, the loss of skeletal muscle mass and function associated with aging. As SMA is correlated...