Muscle growth in the neonatal period may be very sensitive to variations in early nutrition, but little is known about long-term effects of infant feeding on muscle strength. Methods. In 2,983 community-dwelling older men and women born 1931鈥 1939, we examined the relationship between their ...
Sinha-Hikim I, Cornford M, Gaytan H, et al. Effects of testosterone supplementation on skeletal muscle fiber hypertrophy and satellite cells in community-dwelling older men. J Clin Endocrinol Metab 2006; 91 (8): 3024–33 ArticlePubMedCASGoogle Scholar Nygaard E. Skeletal muscle fibre characteri...
With aging and other muscle wasting diseases, men and women undergo similar pathological changes in skeletal muscle: increased inflammation, enhanced oxidative stress, mitochondrial dysfunction, satellite cell senescence, elevated apoptosis and proteasom
The purpose of this study was to determine whether growth hormone (GH) administration enhances the muscle protein anabolism associated with heavy-resistance exercise training in older men. Twenty-three healthy, sedentary men (67 +/- 1 yr) with low serum insulin-like growth factor I levels followe...
the mechanistic role of SCs in growth and repair of CP musculature is not well understood. For instance, it may be that SCs are more pertinent to hypertrophy in young muscle for growth and repair, rather than in older individuals; the role of SCs in regulating fibroblast activity during colla...
Age-related muscle dysfunction and sarcopenia are major causes of physical incapacitation in older adults and currently lack viable treatment strategies. Here we find that sphingolipids accumulate in mouse skeletal muscle upon aging and that both genetic
Imagine that you have a big older brother who you look up to. He's solidly built, with wide, impressive shoulders and powerful legs. He walks with confidence, drive and determination. Anytime you have a questions about life, training or girls he's there for you and tells you exactly wha...
Greater growth hormone and insulin response in women than in men during repeated bouts of sprint exercise. Acta Physiol Scand 2009; 197: 107–115. Article CAS Google Scholar Speranza L, Grilli A, Patruno A, Franceschelli S, Felzani G, Pesce M et al. Plasmatic markers of muscular stress...
Conclusion Higher E-DII score is associated with lower muscle mass and muscle strength, and increased likelihood for the combination of low muscle mass and low muscle strength in older adults. This has important implications for healthy aging.Similar...
Our results indicate that sex differences in adaptations to resistance training are apparent in older adults. However, it is evident that the interpretation of sex-dependent adaptations to resistance training is heavily influenced by the presentation of the results in either an absolute or relative con...