Sliding filament theory ATP binds to a myosin head, which is released from an actin filament Hydrolysis of ATP cocks the myosin head The myosin head attaches to an actin binding site with the help of Calcium The power stroke slides the thin filament when ADP and Pi are released from it Sli...
(a) A schematic diagram of the co-culture system used to evaluate the effect of young functional MDSPCs on dysfunctional MDSPCs isolated from progeroid or old WT mice. Ercc1 − / − MDSPCs were plated in the lower compartment of the transwell system in proliferation media. WT-MDSPCs ...
aUpper panel: Muscle pattern diagram of third-instarDrosophilalarvae. Scale bar, 200 μm. The dashed white box represents the area shown in (b,c”’). Bottom panel: The enlarged area is outlined in the white box in the upper panel for clarity. Scale bar, 100 μm. The arrangement of ...
Figure 7.1.Diagram of the human digestive system from the port-of-entry oral cavity to the exit at the anus. The total length of the digestive system in an adult is ~27ft, or 4.5×the average height of 6ft of an adult. The esophagus is ~10 in in length. The small intestine is ~...
Label free quantification (LFQ) intensity quantifies protein abundance (see “Methods”). b Same as A for astronaut B. c Top, Venn diagram showing the intersection of common proteins with significantly higher expression pre-mission in both astronauts (left sides of volcano plots for astronauts ...
To complement previous two-hybrid screens for the identification of sarcoglycan interactors [25,26], we used a new co-immunoprecipitation (co-IP) and label-free proteomic approach to identify proteins directly or indirectly associated with Sgcg (Fig.1). Eliminating time-consuming ultracentrifugation ...
Figures for amino acid profiling in HME and BME samples by targeted metabolomics analysis. (A): Venn diagram of amino acid composition for HME and BME. (B): Bar chart showing the content of amino acids and their metabolites in HME and BME. (C): Relative abundance heat map of amino acids...
HPASMCs were then stained with 1× Apollo staining solution for 30 minutes to visualize replicating DNA, and 1× 4',6-diamidino-2-phenylindole (DAPI) was used to label cell nuclei. Cell fluorescence images were observed using an Olympus fluorescence microscope (BX53, Tokyo, Japan)....
(right panels).dVenn diagram representing the overlap in differentially expressed proteins between the present study and previous literature utilising young healthy humans23,32,33. The bubble size for each study is proportional to the number of differentially expressed proteins identified (this was not...
eFunctional enrichment analysis with GO Biological Processes analysis using DEGs downregulated (d) and upregulated (e) in DM1 vs control (CTRL) cells. The X-axis represents the –log10(P-value).f,gBubble diagram showing the top 10 Reactome pathways for DEGs downregulated (f) and upregulated...