MULTIOMICSCENTRAL nervous systemHIPPURIC acidSYMPTOMSMETABOLOMICSBackground: Multiple sclerosis (MS), a chronic autoimmune disorder marked by demyelination in the central nervous system, is exceptionally uncommon in China, and remains poorly understood in terms of its peripheral blood...
While individual omics levels may focus exclusively on a single type of cellular component or process, the goal of multi-omics is to integrate omics data from multiple levels in order to identify novel biomarkers, associations and potential treatment targets. Bloehdorn et al. [137] have character...
Therefore, we performed a systematic assessment of invasiveness-related molecular features across multiple human cancers. Materials and methods Multi-omics data, including gene expression, miRNA, DNA methylation, and somatic mutation, in approximately 10,000 patients across 30 cancer types from The ...
Multi-omics analysis of multiple missions to space reveal a theme of lipid dysregulation in mouse liver Afshin Beheshti, Kaushik Chakravarty, Homer Fogle, Hossein Fazelinia, Willian A. da Silveira, Valery Boyko, San-Huei Lai Polo, Amanda M. Saravia-Butler, Gary Hardiman, Deanne ...
In summary, we classified the HCC samples into five subgroups using multiple "-omics" data. Each subgroup had a distinct survival rate and molecular signature, which may provide information about the pathogenesis of subtypes in HCC. 展开
Multiomics analysis reveals a distinct response mechanism in multiple primary lung adenocarcinoma after neoadjuvant immunotherapy 来自 Semantic Scholar 喜欢 0 阅读量: 101 作者:C Zhang,K Yin,SY Liu,LX Yan,XN Yang 摘要: Multiple primary lung cancer (MPLC) remains a tough challenge to diagnose and ...
Here, we present a novel unsupervised single-sample gene-set analysis that calculates an integrated enrichment score using all the information in multiple omics data sets, named “multi-omics GSA” (MOGSA). The method relies on matrix factorization (MF), powerful methods that can be used to le...
Our multi-’omics’ approach discovered panels of multiple biomarkers, reflecting the multifaceted aspects of PE disease, and have the potential both to provide a definitive diagnosis of PE patients and to be used to monitor disease progression....
et al. The KUPNetViz: a biological network viewer for multiple -omics datasets in kidney diseases. BMC Bioinformatics 14, 235 (2013). https://doi.org/10.1186/1471-2105-14-235 Download citation Received12 July 2012 Accepted21 July 2013 Published24 July 2013 DOIhttps://doi.org/10.1186/1471-...
Therefore, integration of multiple layers of information, the multi-'omics' approach, is required to acquire a precise picture of living micro-organisms. In spite of this being a challenging task, some attempts have been made recently to integrate heterogeneous 'omics' datasets in various microbial...